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Grand Challenges is a family of initiatives fostering innovation to solve key global health and development problems. Each initiative is an experiment in the use of challenges to focus innovation on making an impact. Individual challenges address some of the same problems, but from differing perspectives.

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Top Priorities for Maternal, Neonatal, and Child Health in Africa

Grand Challenges Africa
27 Nov 2019

2019 Grand Challenges Annual Meeting Call-to-Action

Grand Challenges
30 Oct 2019

Voices for Economic Opportunity

Grand Challenges
18 Sep 2019
GCE_Round24

Innovations for Improving the Impact of Health Campaigns (Round 24)

Grand Challenges Explorations
18 Sep 2019

Data Science Approaches to Improve Maternal and Child Health in Africa

Grand Challenges Africa
13 Mar 2019

Increasing Demand for Vaccination Services (Round 23)

Grand Challenges Explorations
19 Feb 2019

Environmental niches of Salmonella Typhi (Round 23)

Grand Challenges Explorations
19 Feb 2019

Emerging Technologies for New Solutions in Global Health Priority Areas (Round 23)

Grand Challenges Explorations
19 Feb 2019

Neglected Tropical Diseases Data Innovation Incubator

Grand Challenges
28 Jan 2019

2018 Grand Challenges Annual Meeting Call-to-Action

Grand Challenges
19 Oct 2018

Application of Metagenomic Next Generation Sequencing to Detect and Identify Pathogens (Round 22)

Grand Challenges Explorations
15 Oct 2018

Increasing Demand for Vaccination Services (Round 22)

Grand Challenges Explorations
19 Sep 2018

New Approaches for Manufacturing Gut Microbial Biotherapeutics (Round 22)

Grand Challenges Explorations
19 Sep 2018

Innovation for WASH in Urban Settings (Round 22)

Grand Challenges Explorations
19 Sep 2018

New Approaches for Strategic Prioritization of Agricultural Development Policies (Round 22)

Grand Challenges Explorations
19 Sep 2018

Tools and Technologies for Broad-Scale Pest and Disease Surveillance of Crop Plants in Low-Income Countries (Round 22)

Grand Challenges Explorations
19 Sep 2018

Innovations Driving Programmatic Performance in Immunization: Service Experience and Data Use + Measurement (Round 22)

Grand Challenges Explorations
19 Sep 2018

Data Science Approaches to Improve Maternal and Child Health in India

Grand Challenges India
3 Jul 2018

Grand Challenges Africa: Drug Discovery

Grand Challenges Africa
27 Jun 2018

Ending the Pandemic Threat: A Grand Challenge for Universal Influenza Vaccine Development

Grand Challenges
27 Apr 2018

Grand Challenges India: New Approaches to Characterize the Global Burden of Antimicrobial Resistance

Grand Challenges India
11 Apr 2018

Grand Challenges Explorations - Brazil: New Approaches to Characterize the Global Burden of Antimicrobial Resistance

Grand Challenges Brazil
5 Apr 2018

Grand Challenges Africa: New Approaches to Characterize the Global Burden of Antimicrobial Resistance

Grand Challenges Africa
29 Mar 2018

Grand Challenges South Africa: New Approaches to Characterize the Global Burden of Antimicrobial Resistance

Grand Challenges South Africa
29 Mar 2018

Innovations in Immunization Data Management, Use, and Improved Process Efficiency (Round 21)

Grand Challenges Explorations
5 Mar 2018

Affordable, Accessible, and Appealing: The Next Generation of Nutrition (Round 21)

Grand Challenges Explorations
5 Mar 2018

Tools and Technologies for Broad-Scale Disease Surveillance of Crop Plants in Low-Income Countries (Round 21)

Grand Challenges Explorations
5 Mar 2018

Grand Challenges Explorations - Brazil: Data Science Approaches to Improve Maternal and Child Health in Brazil

Grand Challenges Brazil
5 Mar 2018

Campylobacter spp. Transmission Dynamics in Low- and Middle-Income Countries

Grand Challenges
5 Mar 2018

Saving Lives at Birth (Round 8)

Grand Challenges for Development
10 Jan 2018

Reinventing Teaching and School Leadership: Preparing Youth with the 21st Century Skills Needed for a Knowledge Economy

Grand Challenges
14 Nov 2017

Activating Global Citizenship: Building the Next Generation of Global Citizens for the Global Goals

Grand Challenges
14 Nov 2017
Adolescent Maternal Health

Healthy Minds for Adolescent Mothers: Achieving Healthy Outcomes for the Family (Round 20)

Grand Challenges Explorations
6 Sep 2017
Round 19 - Daignostics

Innovations for Integrated Diagnostics Systems (Round 20)

Grand Challenges Explorations
6 Sep 2017

Novel Approaches for Improving Timeliness of Routine Immunization Birthdose and Healthcare Worker Skill in Low-Resource Settings (Round 20)

Grand Challenges Explorations
6 Sep 2017

Health Systems Strengthening: Ensuring Effective Health Supply Chains (Round 19)

Grand Challenges Explorations
7 Mar 2017

New Approaches for Improving Timeliness of Routine Immunizations in Low-Resource Settings (Round 19)

Grand Challenges Explorations
7 Mar 2017

Wearables and Technology for Maternal, Neonatal and Child Health Behavior Change (Round 19)

Grand Challenges Explorations
7 Mar 2017
Round 19 - Daignostics

Innovations for Integrated Diagnostics Systems (Round 19)

Grand Challenges Explorations
7 Mar 2017

Saving Lives at Birth (Round 7)

Grand Challenges for Development
20 Dec 2016

Grand Challenges Africa - Innovation Seed Grants

Grand Challenges Africa
17 Nov 2016

Accelerate Development of New Therapies for Childhood Cryptosporidium Infection (Round 18)

Grand Challenges Explorations
13 Sep 2016

Develop Novel Platforms to Accelerate Contraceptive Drug Discovery (Round 18)

Grand Challenges Explorations
13 Sep 2016

Design New Solutions to Data Integration for Malaria Elimination (Round 18)

Grand Challenges Explorations
13 Sep 2016

Assess Family Planning Needs, Preferences and Behaviors to Inform Innovations in Contraceptive Technologies (Round 18)

Grand Challenges Explorations
13 Sep 2016

Assess Family Planning Needs, Preferences and Behaviors to Inform Innovations in Contraceptive Technologies and Services (Round 17)

Grand Challenges Explorations
18 Feb 2016

Develop Novel Platforms to Accelerate Contraceptive Drug Discovery (Round 17)

Grand Challenges Explorations
18 Feb 2016

Design New Analytics Approaches for Malaria Elimination (Round 17)

Grand Challenges Explorations
18 Feb 2016

Accelerate Development of New Therapies for Childhood Cryptosporidium Infection (Round 17)

Grand Challenges Explorations
18 Feb 2016

Novel Approaches to Characterizing and Tracking the Global Burden of Antimicrobial Resistance (Round 17)

Grand Challenges Explorations
18 Feb 2016

Explore New Solutions in Global Health Priority Areas (Round 17)

Grand Challenges Explorations
18 Feb 2016

Grand Challenges China: New Interventions for Global Health

Grand Challenges China
2 Feb 2016

Saving Lives at Birth (Round 6)

Grand Challenges for Development
12 Jan 2016

New Interventions for Global Health: Vaccine Manufacturing

Grand Challenges
8 Sep 2015

Explore New Solutions in Global Health Priority Areas (Round 16)

Grand Challenges Explorations
8 Sep 2015

Novel Approaches to Characterizing and Tracking the Global Burden of Antimicrobial Resistance (Round 16)

Grand Challenges Explorations
8 Sep 2015

Addressing Newborn and Infant Gut Health Through Bacteriophage-Mediated Microbiome Engineering (Round 16)

Grand Challenges Explorations
8 Sep 2015

Explore New Ways to Measure Delivery and Use of Digital Financial Services Data (Round 16)

Grand Challenges Explorations
8 Sep 2015

Addressing Newborn and Infant Gut Health Through Bacteriophage-Mediated Microbiome Engineering (Round 15)

Grand Challenges Explorations
26 Feb 2015

Explore New Ways to Measure Delivery and Use of Digital Financial Services Data (Round 15)

Grand Challenges Explorations
26 Feb 2015

Surveillance Tools, Diagnostics and an Artificial Diet to Support New Approaches to Vector Control (Round 15)

Grand Challenges Explorations
26 Feb 2015

New Approaches for Addressing Outdoor/Residual Malaria Transmission (Round 15)

Grand Challenges Explorations
26 Feb 2015

New Ways to Reduce Childhood Pneumonia Deaths Through Delivery of Timely Effective Treatment (Round 15)

Grand Challenges Explorations
26 Feb 2015

Enable Merchant Acceptance of Mobile Money Payments (Round 15)

Grand Challenges Explorations
26 Feb 2015

Saving Lives at Birth (Round 5)

Grand Challenges for Development
9 Feb 2015

All Children Thriving - Brazil

Grand Challenges Brazil
4 Nov 2014

All Children Thriving - India

Grand Challenges India
4 Nov 2014

All Children Thriving - South Africa

Grand Challenges South Africa
4 Nov 2014
Healthy Birth

Creating and Measuring Integrated Solutions for Healthy Birth, Growth, and Development

Grand Challenges
4 Nov 2014

Putting Women and Girls at the Center of Development

Grand Challenges
4 Nov 2014

New Interventions for Global Health

Grand Challenges
4 Nov 2014

Explore New Ways to Measure Brain Development and Gestational Age (Round 14)

Grand Challenges Explorations
8 Sep 2014

New Ways to Reduce Pneumonia Fatalities Through Timely, Effective Treatment of Children (Round 14)

Grand Challenges Explorations
8 Sep 2014

New Ways of Working Together: Integrating Community-Based Intervention (Round 14)

Grand Challenges Explorations
8 Sep 2014

Enable Universal Acceptance of Mobile Money Payments (Round 14)

Grand Challenges Explorations
8 Sep 2014

New Approaches for Addressing Outdoor/Residual Malaria Transmission (Round 14)

Grand Challenges Explorations
8 Sep 2014

Surveillance Tools, Diagnostics and an Artificial Diet to Support New Approaches to Vector Control (Round 14)

Grand Challenges Explorations
8 Sep 2014

New Ways of Working Together: Community-Based Interventions (Round 13)

Grand Challenges Explorations
4 Mar 2014

Inciting Healthy Behaviors: Nudge, Disrupt, Leapfrog, Reach (Round 13)

Grand Challenges Explorations
4 Mar 2014

Explore New Ways to Measure Fetal and Infant Brain Development (Round 13)

Grand Challenges Explorations
4 Mar 2014
Enteric Dysfunction

Novel Enabling Tools and Models Supporting Development of Interventions for Enteric Dysfunction (Round 13)

Grand Challenges Explorations
4 Mar 2014

Innovations in Feedback and Accountability Systems for Agricultural Development (Round 13)

Grand Challenges Explorations
4 Mar 2014

Saving Lives at Birth (Round 4)

Grand Challenges for Development
8 Jan 2014

Reinvent the Toilet

Grand Challenges India
2 Oct 2013

Develop the Next Generation of Condom (Round 12)

Grand Challenges Explorations
5 Sep 2013

Innovations in Feedback and Accountability Systems for Agricultural Development (Round 12)

Grand Challenges Explorations
5 Sep 2013
Enteric Dysfunction

Novel Enabling Tools and Models Supporting Development of Interventions for Enteric Dysfunction (Round 12)

Grand Challenges Explorations
5 Sep 2013

The One Health Concept: Bringing Together Human and Animal Health for New Solutions (Round 12)

Grand Challenges Explorations
5 Sep 2013

Inciting Healthy Behaviors: Nudge, Disrupt, Leapfrog, Reach (Round 12)

Grand Challenges Explorations
5 Sep 2013

Achieving Healthy Growth Through Agriculture and Nutrition

Grand Challenges India
26 Aug 2013

Treatment Adherence for TB

Grand Challenges India
1 Jun 2013

Labor Saving Strategies and Innovations for Women Smallholder Farmers (Round 11)

Grand Challenges Explorations
4 Mar 2013

New Approaches for Detection, Treatment, and Control of Selected Neglected Tropical Diseases (Round 11)

Grand Challenges Explorations
4 Mar 2013

Develop the Next Generation of Condom (Round 11)

Grand Challenges Explorations
4 Mar 2013

The One Health Concept: Bringing Together Human and Animal Health for New Solutions (Round 11)

Grand Challenges Explorations
4 Mar 2013

Increasing Interoperability of Social Good Data (Round 11)

Grand Challenges Explorations
4 Mar 2013

Reducing the Burden of Preterm Birth

Grand Challenges Brazil
26 Feb 2013

Saving Lives at Birth (Round 3)

Grand Challenges for Development
17 Jan 2013

New Approaches in Model Systems, Diagnostics, and Drugs for Specific Neglected Tropical Diseases (Round 10)

Grand Challenges Explorations
5 Sep 2012

Labor Saving Innovations for Women Smallholder Farmers (Round 10)

Grand Challenges Explorations
5 Sep 2012

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