Skip to main content

Grand Challenges

Bill & Melinda Gates Foundation

Main menu

  • About
  • Challenges
  • Awarded Grants
  • News
  • Grant Opportunities
  • Search

You are here

  1. Home
  2. Awarded Grants
  3. 2008
  4. 2015
  5. 2006

Print link

Print

Awarded Grants

Filter by Initiative

  • Grand Challenges Explorations Apply Grand Challenges Explorations filter (226)
  • Grand Challenges Apply Grand Challenges filter (20)
  • Grand Challenges for Development Apply Grand Challenges for Development filter (19)
  • Grand Challenges Brazil Apply Grand Challenges Brazil filter (9)
  • Grand Challenges India Apply Grand Challenges India filter (3)

Filter by Challenge

Filter by Awarded Year

  • 2019 Apply 2019 filter (121)
  • 2018 Apply 2018 filter (129)
  • 2017 Apply 2017 filter (98)
  • 2016 Apply 2016 filter (162)
  • (-) Remove 2015 filter 2015 (171)
  • 2014 Apply 2014 filter (152)
  • 2013 Apply 2013 filter (184)
  • 2012 Apply 2012 filter (244)
  • 2011 Apply 2011 filter (258)
  • 2010 Apply 2010 filter (142)
  • 2009 Apply 2009 filter (157)
  • (-) Remove 2008 filter 2008 (105)
  • (-) Remove 2006 filter 2006 (1)
  • 2005 Apply 2005 filter (43)

Filter by Country

Grand Challenges is a family of initiatives fostering innovation to solve key global health and development problems. Each initiative is an experiment in the use of challenges to focus innovation on making an impact. Individual challenges address some of the same problems, but from differing perspectives.

Sort by:
Date Awarded
Title (A-Z)
10
25
50
100

Testing an Integrated and Innovative Women-Centered Homestead Food Production Model as a Means to Improve Food Security, Nutrition and Women's Empowerment in Cambodia for Future Scale Up

Hou KroeunHelen Keller International (Cambodia)Kampong Cham, Cambodia
Grand Challenges
Women and Girls
22 Dec 2015

Hou Kroeun of the Cambodia office of Helen Keller International will evaluate the additional impact of promoting gender equality on households’ food security and health. They will recruit households spanning 180 rural communities in Kampong Cham Province to evaluate the impact of a gender-transformative Enhanced Homestead Food Production intervention, which will provide agricultural training and resources through primary contact with the female head of household, as well as sessions addressing gender issues with all main-decision makers in the family. They will then test the impact of this women-centered approach on household food security and nutritional status.

Ensure Year-Wise Nutritional Food Security to Indian Women Through Community Level Implementation of Domestic Solar Conduction Dryer

Vaibhav TidkeScience for SocietyAurangabad, , India
Grand Challenges India
Agriculture and Nutrition
15 Dec 2015

The project aims to ensure food-security throughout the entire year in a rural district by storing food through an innovative technology known as the Solar Conduction Dryer. It also aims to add extra income to women farmers from the sale of the dehydrated products of this technology, while providing valuable lessons in post-harvest losses.

Understanding Outcomes of Acutely Ill Undernourished Children

Ezekiel MupereCase Western Reserve UniversityCleveland, Ohio, United States
Grand Challenges
All Children Thriving
11 Dec 2015

GAP Year Program (Girls Achieve Power) - Using Sport to Empower Girls at Critical Time of Adolescent Transition

Saiqa MullickWits Health Consortium (Proprietary) LimitedSouth Africa
Grand Challenges
Women and Girls
3 Dec 2015

Saiqa Mullick of Wits Reproductive Health & HIV Research Institute (RHI) in South Africa, along with Grass Root Soccer (GRS), Sonke Gender Justice, and the Population Council, will empower adolescent girls in South African townships as they progress in education by increasing their educational, health, social, and economic assets, while at the same time shifting gender attitudes and encouraging positive behavior among adolescent boys. The “Girls Achieve Power” (GAP) Year Program will work with schools and communities to encourage a culture of health and safety, and promote school retention among adolescent girls. Using soccer as a program platform, and enlisting local coaches as facilitators, the program will enable a healthy and productive progression for adolescent girls through secondary school. Aside from these direct benefits, the program will also expand the evidence base around the impact of asset-building approaches for adolescent girls.

A Novel Nano-Iron Supplement (IHAT) to Safely Combat Iron Deficiency and Anemia (IDA)

Andrew PrenticeMedical Research CouncilSwindon, United Kingdom
Grand Challenges
Global Health Interventions
30 Nov 2015

Andrew Prentice of the Medical Research Council in the United Kingdom will conduct a phase II clinical trial to test the ability of a unique nano iron compound to safely and more effectively treat iron-deficiency anemia in children. Iron-deficiency anemia is a common condition particularly in women and children in resource-poor settings and can be deadly. Current iron supplements have limited effects in these settings and undesirable side effects including increasing the risk of infectious diarrhea in children which causes severe morbidity and mortality. They previously developed a compound iron hydroxide adipate tartrate that acts like dietary iron as it can be directly absorbed in humans keeping it away from any resident intestinal pathogens that also use it as a nutrient source. They will perform an intervention study with 600 iron-deficient anemic children in The Gambia and compare their compound with the current supplement to see if it can normalize iron levels without the side effects.

Normalizing Tuberculosis Granuloma Vasculature and Matrix to Improve Drug Delivery and Efficacy

Rakesh JainGeneral Hospital CorporationBoston, Massachusetts, United States
Grand Challenges
Global Health Interventions
23 Nov 2015

Rakesh Jain of Massachusetts General Hospital in the U.S. will develop a new treatment strategy for tuberculosis to boost the activity of existing anti-tuberculosis drugs. Tuberculosis is one of the most infectious diseases in the world. Current treatments are lengthy poorly tolerated and do not eradicate latent infections which are found in around one third of the general population and contribute to drug resistance. During latent infection the tuberculosis bacteria are dormant and reside in small inflammatory areas in the lungs known as granulomas. These granulomas are surrounded by abnormal blood vessels and dense tissue that they hypothesize make it difficult for drugs to permeate. They will use a small animal disease model and patient lung samples to test whether co-treatment with anti-angiogenics and anti-fibrotics can normalize the blood vessels and improve the delivery of anti-tuberculosis drugs thereby increasing their activity and potentially shortening treatment duration.

Umodzi - Men, Women, Boys and Girls in Alliance to Achieve Gender Equality

Thokozani MwenyekondeCAREAtlanta, Georgia, United States
Grand Challenges
Women and Girls
19 Nov 2015

Thokozani Mwenyekonde from CARE in Malawi is implementing the Umodzi project to promote gender equality for women and girls by engaging adolescent girls and boys, along with supportive adult male and female role models, to integrate gender equitable attitudes and behavior in schools as a basis for changing attitudes nationwide. Umodzi, which means "oneness" in the local Chichewa language, will build upon and adapt existing gender equality approaches including integrating efforts into the school curriculum, training teachers who convene teen club meetings, and working with adults who are also engaged in CARE's pro-women agriculture and savings programs in the school catchment areas.

Digital Sub-Wallets for Increased Financial Empowerment of Women

Lauren HendricksCAREAtlanta, Georgia, United States
Grand Challenges
Women and Girls
19 Nov 2015

Lauren Hendricks and team at CARE in Uganda will analyze whether motivating women to use mobile financial technology increases their involvement in making household financial decisions, and subsequently improves family health and education. They will develop mobile money subwallets for specific purposes such as school fees and pregnancy so that women can more securely manage their savings. They will also work with influential members of a subset of households to help promote gender equality and develop a consensus towards a household financial action plan.

Promoting Female Empowerment at the Household Level with Family Planning Use, Financial Literacy and Gender Sensitization Education Among Couples in Ibadan, Nigeria

Funmilola OlaOlorunUniversity of Ibadan, College of MedicineIbadan, Nigeria
Grand Challenges
Women and Girls
18 Nov 2015

Funmilola OlaOlorun of the University of Ibadan in Nigeria and Neetu John of the International Center for Research on Women, in the U.S. will conduct a cluster randomized control trial to evaluate a multi-pronged approach for empowering Nigerian women within the household and thereby the wider community. Their program targets both partners of couples, both individually and together, and involves training on gender socialization and finance, and access to family planning. The aim is to generate rigorous evidence on how to promote gender equality in household decision-making and improve family health and wellbeing.

A Synthetic Biology Platform for Rapid Generation of Highly Diverse Natural Product-Like Compounds Active Against Mycobacterium tuberculosis

Mike TyersUniversité de MontréalMontreal, Quebec, Canada
Grand Challenges
Global Health Interventions
18 Nov 2015

Michael Tyers of the University of Montreal in Canada will develop a synthetic biology platform to generate vast libraries of natural product-like compounds and use them to identify new drugs for tuberculosis. Traditional drug discovery screens require expensive chemical libraries that are limited in size and scope. Many existing drugs are derived from the natural products of microbes which perform a wide variety of biological functions. This functional diversity is reflected by their structural diversity which is generated by the combinatorial action of hundreds of thousands of different enzymes. They will exploit this natural manufacturing process for the relatively simple and low-cost production of millions to billions of chemically-diverse natural product-like compounds. This will be achieved by expressing different combinations of the enzymes in yeast artificial chromosomes which then allows screening directly in the yeast without the need for costly and time-consuming chemical extraction and purification. Using this approach they will perform a pilot screen to identify new compounds that inhibit the growth of the bacterium that causes tuberculosis.

Pages

  • Currently on page 1
  • Page 2
  • Page 3
  • Page 4
  • Page 5
  • Page 6
  • Page 7
  • Page 8
  • Page 9
  • …
  • Next page
  • Last page
Sort by:
Date Awarded
Title (A-Z)
10
25
50
100

Contact us

Contact us

  • General Inquiries
  • Media Inquiries

Footer - Receive Updates

Receive updates

  • Sign up for email updates

Footer

  • Privacy Policy and Terms of Use
© 2003-2019. Grand Challenges. All Rights Reserved.

PLEASE REVIEW OUR UPDATED PRIVACY & COOKIES NOTICE

This site uses cookies and similar technologies to store information on your computer or device. By continuing to use this site, you agree to the placement of these cookies and similar technologies. Read our updated Privacy & Cookies Notice to learn more.