Skip to main content

Grand Challenges

Bill & Melinda Gates Foundation

Main menu

  • About
  • Challenges
  • Awarded Grants
  • News
  • Grant Opportunities
  • Search

You are here

  1. Home
  2. Awarded Grants
  3. 2013
  4. 2006
  5. Grand Challenges
  6. 2016

Print link

Print

Awarded Grants

Filter by Initiative

  • (-) Remove Grand Challenges filter Grand Challenges (30)

Filter by Challenge

Filter by Awarded Year

  • 2019 Apply 2019 filter (23)
  • 2018 Apply 2018 filter (16)
  • (-) Remove 2016 filter 2016 (26)
  • 2015 Apply 2015 filter (19)
  • 2014 Apply 2014 filter (1)
  • (-) Remove 2013 filter 2013 (3)
  • 2012 Apply 2012 filter (22)
  • 2011 Apply 2011 filter (25)
  • (-) Remove 2006 filter 2006 (1)
  • 2005 Apply 2005 filter (43)

Filter by Country

Grand Challenges is a family of initiatives fostering innovation to solve key global health and development problems. Each initiative is an experiment in the use of challenges to focus innovation on making an impact. Individual challenges address some of the same problems, but from differing perspectives.

Sort by:
Date Awarded
Title (Z-A)
10
25
50
100

Plan-It Girls: Empowerment, Employability and Entrepreneurship for Older Adolescent Girls in India

Priya NandaInternational Center for Research on WomenWashington, District of Columbia, United States
Grand Challenges
Women and Girls
12 Jul 2016

Priya Nanda of the International Center for Research on Women in the U.S. will help young women in India secure decent employment and raise healthy families by giving adolescent girls access to relevant skills, resources, and connections, and engaging schoolboys and male community members to promote gender equality. They will recruit teachers to implement a specialized curriculum in schools, and connect with local businesses to create pathways to employment. Providing women with access to work should improve family health and income as well as promote economic growth and development.

Population-Based Indicators of Early Child Development

Susan WalkerUniversity of the West IndiesKingston, Jamaica
Grand Challenges
All Children Thriving
29 Feb 2016

Preventing Preterm Birth in Zambia

Jeffrey StringerUniversity of North Carolina at Chapel HillChapel Hill, North Carolina, United States
Grand Challenges in Global Health
Preventing Preterm Birth
1 Oct 2013

Jeffrey Stringer of the University of North Carolina Global Women’s Health group in the U.S. will oversee a team of Zambian and U.S. researchers in a prospective cohort study of 2,000 pregnant women over a three-year period in Lusaka, Zambia. The study will assess gestational age by early ultrasound and collect data and specimens throughout pregnancy and at delivery with standardized systems to document complications of pregnancy and assessment of birth outcomes. Data and specimens will be used to evaluate the causes of preterm birth and investigate novel strategies for prevention.

RINEW: Research on Integration of Nutrition Early Childhood Development WASH

Mahbubur RahmanInternational Centre for Diarrhoeal Disease Research, BangladeshDhaka, Bangladesh
Grand Challenges
All Children Thriving
20 Jul 2016

Room to Grow

Léger FoyetPopulation Services InternationalWashington, District of Columbia, United States
Grand Challenges
Women and Girls
11 Oct 2016

Léger Foyet of Population Services International in the U.S. along with the Organization to Advance Solutions in the Sahel (OASIS) and the High Commission of the Nigeriens Nourish Nigeriens agriculture initiative (HC3N) will improve gender equity, nutrition, and access to family planning in Niger. Niger has one of the highest levels of poverty and malnutrition. Women in Niger are usually married before the age of 16 and have on average around eight children. Men generally make the decisions on family planning, and there is limited access to contraceptives and healthcare. Non-governmental organizations have supported over 3,000 community gardens across Niger that use solar-powered drip irrigation for growing basic crops like beans. The gardens are tended daily by women, providing an opportunity to address gender inequality in a safe and supportive space. They will select up to 20 gardens to develop and test a package of successful interventions targeting both women and men including reproductive health counseling, identifying gender-based barriers to family planning, and engaging religious leaders to help overturn deep-seated social norms.

Saving Lives with Better Gestational Age Estimation: Improving the Accuracy of Recall and Reporting of the Date of Last Menstrual Period (LMP) in Rural Bangladesh

Shumona Sharmin SalamInternational Centre for Diarrhoeal Disease Research, BangladeshDhaka, Bangladesh
Grand Challenges
All Children Thriving
4 May 2016

Segmented Filamentous Bacteria as a Vaccination Platform to Protect Young Children Against Enteric Pathogens

Pamela SchnupfParis Descartes UniversityParis, France
Grand Challenges
Global Health Interventions
15 Nov 2016

Pamela Schnupf of Paris Descartes University in France will develop an oral vaccine to prevent infectious diarrhea in children by engineering a non-pathogenic bacteria to express pathogen molecules that can be safely delivered in bacterial spores. Diarrheal disease caused largely by Shigella and enterotoxigenic Escherichia coli is a major cause of morbidity and mortality in children under five years of age in low-resource settings. Segmented filamentous bacterium (SFB) is non-pathogenic and normally colonizes the human gut during infancy and stimulates the immune system to protect against infections. They will establish methods to genetically engineer SFB to express selected antigens from enterotoxigenic E.coli and test whether it can stimulate an immune response and protect against infection using established mouse models.

Strengthening Livelihood Strategies of Vulnerable Women in the DR Congo

Kanigula MubagwaPanzi FoundationBukavu, Congo (Kinshasa)
Grand Challenges
Women and Girls
29 Sep 2016

Kanigula Mubagwa of the Panzi Foundation in DR Congo will test whether providing resources that simultaneously improve nutrition, income, and social status can help women and girls getting out of prostitution in the cities of DR Congo successfully reintegrate into more rural societies. Prostitutes and their families suffer from high levels of poverty and malnutrition. Individual strategies to support them often provide only temporary solutions. To address this, they will combine a variety of tested interventions including providing agricultural training, nutritional education, and access to crops and equipment, and engage men and prominent local people to transform social norms. They will recruit ex-prostitutes from Salvation Army Centers to evaluate their approach for improving participants' knowledge and skills in agriculture, nutrition and health, and for promoting gender equality in their communities.

Systems Biology of Preterm Birth: A Pilot Study

Stephen LyeMount Sinai HospitalToronto, Ontario, Canada
Grand Challenges in Global Health
Preventing Preterm Birth
1 Feb 2013

Stephen Lye at Mount Sinai Hospital in Canada and his team will initiate a pilot study that will use a systems biology analysis of genomic, proteomic and plasma markers to identify novel pathways and biomarkers to preterm birth, as well as define the risk of preterm birth in pregnant women. Previous efforts to identify pathways or biomarkers associated with preterm birth have focused on single methodological approaches. With new capabilities in computational analyses, it is now possible to integrate information from multiple analytic techniques – collectively known as systems biology – to derive informative pathways and potential diagnostic biomarkers.

Ultra Low-cost Transferable Automated (ULTRA) Platform for Vaccine Manufacturing

Tarit MukhopadhyayUniversity College LondonLondon, United Kingdom
Grand Challenges
Vaccine Manufacturing
18 Nov 2016

Tarit Mukhopadhyay of University College London in the United Kingdom will develop a manufacturing platform to reduce the production costs of recombinant protein vaccines. Current manufacturing procedures involve serial batch operations in large complex facilities requiring highly trained operators and extensive testing and are inefficient and costly. They will build a platform that integrates and automates key steps to reduce labor costs and capital expenditure and improves product design and control procedures to reduce quality control requirements. Their aim is to maximize the number of doses with the minimal starting material leading to recombinant subunit vaccines at 0.15USD per dose rather than the current costs of several USD per dose. They will develop their approach initially using a rotavirus vaccine candidate.

Pages

  • First page
  • Previous page
  • Page 1
  • Page 2
  • Currently on page 3
Sort by:
Date Awarded
Title (Z-A)
10
25
50
100

Contact us

Contact us

  • General Inquiries
  • Media Inquiries

Footer - Receive Updates

Receive updates

  • Sign up for email updates

Footer

  • Privacy Policy and Terms of Use
© 2003-2019. Grand Challenges. All Rights Reserved.

PLEASE REVIEW OUR UPDATED PRIVACY & COOKIES NOTICE

This site uses cookies and similar technologies to store information on your computer or device. By continuing to use this site, you agree to the placement of these cookies and similar technologies. Read our updated Privacy & Cookies Notice to learn more.