The Center for Popular Democracy's Fair Workweek Initiative in the U.S. will run a digital campaign to tell the real-life stories of how volatile working hours and other business practices harm families' financial security and well-being. The majority of Americans are paid hourly and are not given set working hours. This makes it difficult for families to plan for necessities such as child-care or pursue further education, leading to poverty, instability, and a feeling of powerlessness. These practices are prevalent in low-wage jobs (often considered "essential"), occupied by workers of color, especially women of color, and perpetuate racial and economic inequities in economic opportunity. Center for Popular Democracy will recruit storytellers, including workers impacted by just-in-time scheduling, and will pair their stories with data to illustrate a larger trend, and highlight how racial bias ensures workers of color experience disproportionate impacts. They will tailor the content to a variety of audiences and evaluate their reactions to different formats.

YR Media in the U.S. will support young people in describing how their lives have been affected by foster care and the juvenile justice system to counter stereotypes and engage diverse audiences. Young people living in poverty are at greater risk of interacting with these systems, both of which often further perpetuate poverty. Their personal reflections will provide powerful illustrations of the complex causes of poverty and the widespread impact it has while also highlighting affected youth's resilience and strength. These insights, when paired and shared, are expected to disrupt deeply entrenched stereotypes. Using their approach and network, YR Media will produce personal narratives as well as social media content for distribution via their youth-run platform and partners.

The National Domestic Workers Alliance in the U.S. will produce a video series portraying the home lives of domestic workers to showcase the important, unique, complex nature of domestic work and create a sense of urgency for policy and employer change that protects domestic workers and expands their economic opportunities (especially in light of the COVID-19 pandemic). There are over 2.5 million domestic workers in the U.S., who are disproportionately women of color and immigrants. Although nannies, housekeepers, and caregivers provide many families with stability and financial security, paradoxically they are not afforded the same. Instead, they deal with poverty-level wages, restricted health coverage and sick pay, and other working conditions that create barriers to economic opportunity. National Domestic Workers Alliance will identify values-based statements that most strongly resonate with key audiences and train domestic workers from diverse backgrounds to shoot videos documenting their lives. The videos will incorporate additional relevant materials and be disseminated through social media.

Stephan Sieber of the Technical University of Munich in Germany will work together with Véronique Dartois of Hackensack Meridian Health in the U.S. to test whether his new antibiotic, which uniquely activates, as well as inactivates, molecular pathways to destroy certain pathogenic bacteria, can be adapted to kill the related Mycobacterium tuberculosis (Mtb), which causes tuberculosis. Current antibiotic treatments are lengthy, and it remains difficult to completely destroy all the bacteria in the body. More worryingly is that Mtb has been developing resistance to these antibiotics, which all work in similar ways, so in some patients they are useless. They have discovered a new antibiotic that works differently: it inactivates bacterial menaquinone biosynthesis but also uniquely activates a signal peptidase to boost its secretory function. In the laboratory, this antibiotic notably bypasses the development of resistance and even kills dormant bacteria, likely by its activating mechanism. They will investigate its mechanism of action in Mtb using affinity-based protein profiling and use that knowledge to select related compounds that might work better in people. These will then be tested in a mouse model of tuberculosis as a first step towards clinical development.