Grand Challenges Explorations - India was launched as a BIRAC India initiative in partnership with the Government of India’s Department of Biotechnology and the Bill &amp; Melinda Gates Foundation as funding partners and IKP Knowledge Park as implementation partner. Aligned with the challenges under Grand Challenges Explorations, its goal is new drugs, vaccines, delivery systems, diagnostics, medical devices, and service models that can be made available to people from all socioeconomic strata. Grand Challenges Explorations - India aims to address this goal by encouraging entrepreneurship in India.

Grand Challenges Explorations - India was launched as a BIRAC India initiative in partnership with the Government of India’s Department of Biotechnology and the Bill &amp; Melinda Gates Foundation as funding partners and IKP Knowledge Park as implementation partner. Aligned with the challenges under Grand Challenges Explorations, its goal is new drugs, vaccines, delivery systems, diagnostics, medical devices, and service models that can be made available to people from all socioeconomic strata. Grand Challenges Explorations - India aims to address this goal by encouraging entrepreneurship in India.

India-GCE

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Grand Challenges Explorations - India is a BIRAC India initiative with the Government of India’s Department of Biotechnology and the Bill &amp; Melinda Gates Foundation as funding partners and <a href="https://ikpgrantprograms.org/gce-india/" target="_blank" rel="noopener noreferrer">IKP Knowledge Park</a> as implementation partner. Aligned with the challenges under Grand Challenges Explorations, it fosters entrepreneurship in India with the goal of new drugs, vaccines, delivery systems, diagnostics, medical devices, and service models that can be made available to people from all socioeconomic strata.

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Grand Challenges Explorations - India

Environmental exposure to antibiotics is correlated well with AMR. The present study proposes the development of high throughput screening (HTS) technique of 125 antibiotics from environmental samples like water (from river, aquifers and food sources like egg and raw meat). A novel in-vitro method will be adopted to correlate AMR with the environmental levels of antibiotics found in Delhi-NCR region and derive safe levels of antibiotics that should be permissible in the environment.

Environmental exposure to antibiotics is correlated well with AMR. The present study proposes the development of high throughput screening (HTS) technique of 125 antibiotics from environmental samples like water (from river, aquifers and food sources like egg and raw meat). A novel in-vitro method will be adopted to correlate AMR with the environmental levels of antibiotics found in Delhi-NCR region and derive safe levels of antibiotics that should be permissible in the environment.

High Throughput Technology to Monitor Environmental Antibiotic Dispersion and Their Impact On AMR

The Inali Arm solves a problem that derails the lives of millions of people across the world. India alone is home to more than 22 million people with disabilities, with children making up nearly 8 million of that number. Due to cost and lack of accessibility, most of these people never get the help they need. The proposal intends to develop indigenous low-cost, affordable arm to for thousands of people who are living without any prosthetic care.

The Inali Arm solves a problem that derails the lives of millions of people across the world. India alone is home to more than 22 million people with disabilities, with children making up nearly 8 million of that number. Due to cost and lack of accessibility, most of these people never get the help they need. The proposal intends to develop indigenous low-cost, affordable arm to for thousands of people who are living without any prosthetic care.

Inali Arm – A Low-Cost Affordable Prosthetic Arm

Studies promoting egg consumption among women and children in lower middle-income countries (LMICs) show that growth indicators are significantly improved in children who consume eggs consistently. However, many states in India are chronically egg deficit, unable to fulfil their daily egg demand. The study is exploring the use of powdered-eggs in place of fresh eggs as they are cheaper and have a longer shelf life. Furthermore, the product is convenient to use, easy to transport, store and can be incorporated as an ingredient into Indian recipes and daily diets.

Studies promoting egg consumption among women and children in lower middle-income countries (LMICs) show that growth indicators are significantly improved in children who consume eggs consistently. However, many states in India are chronically egg deficit, unable to fulfil their daily egg demand. The study is exploring the use of powdered-eggs in place of fresh eggs as they are cheaper and have a longer shelf life. Furthermore, the product is convenient to use, easy to transport, store and can be incorporated as an ingredient into Indian recipes and daily diets.

Powdered Egg: Improving Egg Consumption in India

Wireless Capsule Endoscopy (WCE) has the potential to become the leading screening technique for the entire gastrointestinal (GI) tract. Till date, no Artificial Intelligence (AI) based diagnostic aid has been developed to assist endoscopists in identification and classification of abnormalities post the WCE procedure. The core objective of this proposal is to deliver a first-of-its-kind, multi-platform, AI-powered, fully automated diagnostic web application for real-time detection and classification of multiple abnormalities (angioectasias, aphthae, bleeding, chylous cysts, villous oedema, lymphangiectasia, polypoids, stenosis and ulcers).

Wireless Capsule Endoscopy (WCE) has the potential to become the leading screening technique for the entire gastrointestinal (GI) tract. Till date, no Artificial Intelligence (AI) based diagnostic aid has been developed to assist endoscopists in identification and classification of abnormalities post the WCE procedure. The core objective of this proposal is to deliver a first-of-its-kind, multi-platform, AI-powered, fully automated diagnostic web application for real-time detection and classification of multiple abnormalities (angioectasias, aphthae, bleeding, chylous cysts, villous oedema, lymphangiectasia, polypoids, stenosis and ulcers).

AI-Based Diagnostic Aid for Wireless Capsule Endoscopy

The study proposes a novel low-cost health monitor with 4 components. The first component is a vibration sensor pad which when placed under the mattress detects heart and respiration signal using ballistocardiograph. The respiration signal obtained is also used for sleep apnea screening and the heart signal is also screened for arrhythmia instances and monitoring cardiac cycles (LVET, ICT, IRT). The second component is a bedside unit for data acquisition, processing &amp; communication (GSM &amp; WiFi) with alert system. The third component is a bluetooth enabled wireless finger pulse oximeter to measure oxygen saturation. The final component is a wearable 3D axis accelerometer for fall detection. This data is available in Realtime to the geriatric caregivers who can also setup and receive customized alerts for abnormal vitals signs and fall. The proposed solution is a novel low-cost easy-to-use health monitor that tracks heart and respiration rate, sleep cycles, cardiac cycles, oxygen saturation and detects fall.

The study proposes a novel low-cost health monitor with 4 components. The first component is a vibration sensor pad which when placed under the mattress detects heart and respiration signal using ballistocardiograph. The respiration signal obtained is also used for sleep apnea screening and the heart signal is also screened for arrhythmia instances and monitoring cardiac cycles (LVET, ICT, IRT). The second component is a bedside unit for data acquisition, processing &amp; communication (GSM &amp; WiFi) with alert system. The third component is a bluetooth enabled wireless finger pulse oximeter to measure oxygen saturation. The final component is a wearable 3D axis accelerometer for fall detection. This data is available in Realtime to the geriatric caregivers who can also setup and receive customized alerts for abnormal vitals signs and fall. The proposed solution is a novel low-cost easy-to-use health monitor that tracks heart and respiration rate, sleep cycles, cardiac cycles, oxygen saturation and detects fall.