Skip to main content

Grand Challenges

Bill & Melinda Gates Foundation

Main menu

  • About
  • Challenges
  • Awarded Grants
  • News
  • Grant Opportunities
  • Search

You are here

  1. Home
  2. Challenges

Print link

Print

Discover Biomarkers of Tuberculosis

Grand Challenges in Global HealthDate open: 1 Feb 2011Date closed: 1 Dec 2012 - 4:00am PST
Discover Biomarkers of Health and Disease

Background

High-throughput approaches to genomics, proteomics, and metabolomics have identified diverse candidate biomarkers of health and disease. Validated biomarkers coupled with new technologies for miniaturization and highly parallel detection could enable radically new ways to diagnose health and disease states in an individual, even in remote or impoverished settings.

Roadblock

Lack of accurate and sensitive biomarkers appropriate for point-of-care assessment tools in the developing world means that many health risks and illnesses remain poorly defined and receive inappropriate treatment. In addition, little information about the burden of disease is available to guide population health decisions.

Challenge

To discover and validate biomarkers for use in simple, low-cost tests appropriate for achieving definitive point-of-care assessment of health and disease states in individuals in developing world settings.

Share This Challenge

  • Twitter logo Twitter
  • Facebook logo Facebook
  • LinkedIn logo LinkedIn
  • Google+ logo Google+
  • Mailto logo Mailto

Awarded Grants

Cell Wall Glycan Biomarkers for Tuberculosis
SOMAmer-based Detection of Tuberculosis Biomarkers
Modified DNA Aptamer Affinity Reagents for Mtb Biomarker Validation
Ultra-Sensitive Proteomic Quantitation of Circulating TB Biomarker Candidates by Complete Proteome SRM Assays
Permeable Magnetic Nanoparticles for Point-Of-Care TB Diagnosis

See full list

Contact us

Contact us

  • General Inquiries
  • Media Inquiries

Footer - Receive Updates

Receive updates

  • Sign up for email updates

Footer

  • Privacy Policy and Terms of Use
© 2003-2019. Grand Challenges. All Rights Reserved.

PLEASE REVIEW OUR UPDATED PRIVACY & COOKIES NOTICE

This site uses cookies and similar technologies to store information on your computer or device. By continuing to use this site, you agree to the placement of these cookies and similar technologies. Read our updated Privacy & Cookies Notice to learn more.