Modified DNA Aptamer Affinity Reagents for Mtb Biomarker Validation
Dan Feldheim of the University of Colorado at Boulder in the U.S. and collaborators Bruce Eaton of the University of Colorado and Delphi Chatterjee of Colorado State University propose to develop new modified DNA aptamer affinity reagents for detecting urine biomarkers of M. tuberculosis active disease. These reagents could form the basis of low-cost, low-power diagnostic sensors for use in resource-limited settings.