Using TBK1, a Novel Molecule Which Controls the Adjuvancticity of DNA Vaccines, to Improve DNA Vaccine Immunogencity against Malaria

DNA vaccines, which can elicit killer T-cell response, have thus far failed to elicit reliable, strong immune response in humans. Cevayir Coban of Osaka University in Japan will use newly identified intracellular signaling molecules as components of DNA vaccines against malaria.