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Targeted Capture of Latent M. Tuberculosis Cells from a Mammalian Host

In an attempt to capture and study latent tuberculosis cells, which are reservoirs of infection and highly resistant to treatment, Kim Lewis of Northeastern University will pulse-label tuberculosis cells with green fluorescent protein. While active cells divide and dilute the GFP, latent cells, which are dormant, will remain bright green, allowing for their observation and tracking.

More information about Explore the Basis of Latency in Tuberculosis (Round 1)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.