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Systematic Modulation of Poliovirus Attenuation by Deoptimization of Codon Usage

Olen Kew of the Centers for Disease Control and Prevention in the U.S. will attempt to develop a safe and effective polio strain for use in an inactivated vaccine by modifying codon usage patterns in polio strains to control viral mutation rates, lower infectivity, and raise genetic stability.

More information about Create New Ways of Protecting Against Infectious Diseases (Round 1)