Prevent HIV Infection by Naturally Occurring Antivirals
To harness a woman's immune system to prevent HIV-1 infection, John Fahey and Charles Wira at Dartmouth Medical School in the U.S. will identify SERMs (selective estrogen receptor modulators) similar to those used for treating breast cancer and osteoporosis that can induce local immune protection in the reproductive tract against HIV without compromising normal reproductive function or increasing the risk of HIV infection.