• About
  • Partnerships
  • Challenges
  • Awards
  • Grant Opportunities
  • News

Performance of an Innovative, Instrument-Free, Low-Cost, Rapid Point-of-Care CD4 Test for Accelerating Initiation of Antiretroviral Interventions for HIV 1-Infected Pregnant Women in Resource-Constrained Settings

A simple and accurate instrument-free, low-cost Point-of-Care CD4 test that is applicable in poor, hard-to-reach settings could sustainably increase uptake of antiretroviral intervention and reduce loss to follow-up associated with centralized laboratory-based testing. Four antenatal care clinics in Kenya and South Africa will enroll 275 HIV-infected pregnant women to prospectively assess the accuracy of the novel, rapid, inexpensive ($1.50) and instrument-free Burnet Point-of-Care CD4 test as performed by nurse-midwives in field settings, compared to a WHO pre-qualified POC CD4 instrument-based (PIMA) and a laboratory-based flow cytometric assay. If proven accurate in field settings, the Burnet Point-of-Care CD4 test could be rapidly scaled-up and markedly enhance care, particularly in rural areas of resource-constrained settings.

More information about Saving Lives at Birth (Round 2)

Great ideas come from everywhere.

Sign up for email updates of the latest grant opportunities and awards.

View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.