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Nasal Spray Immunization Against Polio

Anthony van den Pol of Yale University in the U.S. proposes to engineer a highly immunogenic virus to express replication-restricted poliovirus proteins for use in a new nasal spray polio vaccine. The spray will then be tested for its ability to generate a strong immune response against the virus and refined to increase its shelf life at room temperature.

More information about The Poliovirus Endgame: Create Innovative Ways to Accelerate, Sustain, and Monitor Eradication (Round 7)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.