Large-Scale MHC Epitope Analysis for Vaccine Development

Gustavo Fioravanti Vieira of Universidade Federal do Rio Grande do Sul in Brazil will create 3-D computer models of viral epitopes anchored to major histocompatibility complex (MHC) molecules associated with different MHC alleles to search for "generalist" epitopes. Such epitopes can be used to develop viral vaccines that are effective against a broad spectrum of pathogens.