Intestinal Microbiome and Oral Polio Vaccine Immune Response

David Relman of Stanford University in the U.S. will work with collaborators to study the compositions of intestinal microbial communities in children given the oral polio vaccine (OPV). By identifying the gut microbial characteristics of those who display a low response to OPV, Relman and his team can identify predictors of response to the oral vaccine and target children who may need additional dosing and follow-up.