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Inhibition of Octopamine Biosynthesis in Invertebrates

The neurotransmitter octopamine is unique to the invertebrate nervous system and plays a crucial role in invertebrate behavior and fertility. Mark Alkema of the University of Massachusetts in the U.S. will attempt to design drugs to disrupt the biosynthesis of octopamine as a new strategy to interfere with the lifecycle of invertebrate parasites.

More information about Create New Ways of Protecting Against Infectious Diseases (Round 2)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.