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High-Resolution Genome Based Tracing of Antimicrobial Resistant Escherichia Coli in Pork Production Chain to Identify the Critical Control Points: A One Health Systems Study

The project intends to quantitatively assess the dynamics of antimicrobial resistant AMR E.coli across the pork-value-chain in three different states, Tamil Nadu, Karnataka and Meghalaya to identify critical control points of entry and exit of AMR E.coli to design a relevant Hazard Analysis and Critical Control Points (HACCP). Three aspects: rapid ethnographic survey, assessment of pathogen levels at different points of production, through phenotypic and molecular characterisation of isolates for presence or absence of AMR genes proposes to develop a biomarker-based blood test to rapidly discriminate between viral and bacterial infections. The test will aid stewardship efforts by reducing the indiscriminate use of antibiotics for all suspected infections

More information about Grand Challenges India: New Approaches to Characterize the Global Burden of Antimicrobial Resistance

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.