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Environmental Enteropathy in Zambia: Biomarkers Defined by Pathogenesis

Paul Kelly of Queen Mary and Westfield College in the United Kingdom and the University of Zambia will work with colleagues to identify and evaluate candidate biomarkers of environmental enteropathy, which causes growth failure in children in the developing world. Possible markers of enteropathy in serum and gut secretions will be correlated with two severe clinical outcomes, impaired nutrient absorption, and loss of gut barrier function leading to bacteria entering the bloodstream. The aim is to drive the development of new treatments.

More information about Discover Biomarkers of Gut Function

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.