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Block Malarial Transmission by Targeting Gametocyte Activation

To interrupt reproduction of the malaria parasite in the mosquito gut, Greg Garcia and Sheetij Dutta of Walter Reed Army Institute of Research seek to identify and block a gametocyte stage receptor for xanthreunic acid, which is known to trigger the differentiation of gametocytes, an essential step in the life-cycle of the malaria parasite.

More information about Create New Ways of Protecting Against Infectious Diseases (Round 1)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.