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Adenoviral HIV Vaccine Vector with CMV-Like Immunogenicity

Matt Cottingham of The Jenner Institute at the University of Oxford in the United Kingdom will work to engineer an adenovirus vaccine vector that includes HIV antigens as well as the immune evasion genes of cytomegalovirus (CMV). Such a vector could be used in an HIV vaccine to elicit the strong immune response typical of a CMV-vectored vaccine, but without the typical safety issues that accompany the use of CMV in vaccines.

More information about Apply Synthetic Biology to Global Health Challenges (Round 7)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.