The Bill & Melinda Gates Foundation (the Gates Foundation) and the National Natural Science Foundation of China (NSFC) is launching a new Grand Challenge: New Interventions for Global Health. This challenge focuses on calls for innovative concepts for safe, effective, affordable and widely utilized interventions, such as vaccines and therapeutics, with the potential to protect against the acquisition, progression or transmission of infectious diseases that disproportionately affect the world’s poorest. This request for proposals will fund grants to collaborations comprised of teams at Chinese-based institutions and those based outside of China. Each grant must be for four years, and can be up to USD $1,000,000. For each proposal the NSFC will fund up to USD $500,000 for the work done at China-based institutions, and the Gates Foundation will fund up to USD $500,000 for the work done at institutions outside China. The collaborations between groups must be substantive in that they should propose continuous and stable cooperation on the proposed project, the groups should complement each other with their respective strengths and expertise, and the contributions between groups should be roughly equal. The application deadline is March 15, 2016, 8:00am Beijing time (March 14, 2016, 5pm Seattle time). For a detailed description of this challenge, see the Request for Proposals to the right, including translated versions.