Gates Foundation
  • Grant Opportunities
  • Partnerships
  • Systems

Establishment of an African Procurement and Supply Chain Observatory for Public Health and R&D Reagents and Laboratory Supplies

Establishment of an African Procurement and Supply Chain Observatory for Public Health and R&D Reagents and Laboratory Supplies

Before applying to this Grand Challenges request for proposals (RFP), applicants should familiarize themselves with the supporting documents, including the terms and conditions of the Gates Foundation, the Rules and Guidelines, Application Instructions, and Frequently Asked Questions.

If you are planning to apply to this RFP, we will be hosting a dedicated webinar on April 29, 2026, from 8:00-9:00 AM Pacific Time. This session will provide a comprehensive overview of the RFP details and an opportunity to answer your questions. To participate in the webinar, please register and submit your questions in advance. If you are unable to attend live, we will record the webinar and make it available on this challenge page after the session.

Background

Public health and R&D institutions across Africa face persistent, systemic challenges in procuring essential laboratory equipment, reagents, consumables, and related services. The market for these products and services suffers from fragmented demand, inadequate forecasting, limited market visibility, complex and inconsistent regulatory processes, inflated prices, and a lack of reliable and timely after-sales support. These inefficiencies can drive high costs, extended lead times, frequent stock-outs, and missed research and public health surveillance milestones.

In June 2025, Science for Africa Foundation convened a diverse set of stakeholders, including researchers, manufacturers, suppliers, distributors, and digital and technical experts for a two-day design workshop. This meeting identified four priority challenges and proposed solution areas:

  • Challenge I: Demand consolidation and market visibility; alternative procurement models
  • Challenge II: Local manufacturing and uptake
  • Challenge III: Trade facilitation and customs harmonization
  • Challenge IV: Innovative sample transportation

As a follow-up to the June stakeholder convening, the Science for Africa Foundation (SFA), in partnership with the Gates Foundation and Wellcome, is launching the African R&D Procurement and Supply Chain Initiative, a coordinated portfolio of efforts aimed at strengthening Africa’s research and innovation ecosystem. The initiative initially focuses on pathogen genomics as a pilot use case. As a cornerstone component of this, Wellcome will be supporting SFA to convene key African organizations and global stakeholders to develop an implementation-ready blueprint for an Africa-anchored Observatory with pathogen genomics supply chain as a use case. With this RFP, the Gates Foundation will fund its implementation.

This RFP and the broader initiative build on a range of existing procurement and supply chain platforms and initiatives. While these platforms have delivered or are delivering important impact, they were not designed to address several persistent system‑level challenges across the full spectrum of public health and R&D. These include the absence of consolidated demand intelligence across institutions and countries, limited visibility into pricing and lead‑time variability, fragmented supplier and product information, and a lack of coordinated market‑shaping analytics. As a result, institutions continue to face high and inconsistent prices, long lead times, and insufficient transparency. This RFP directly targets these unmet gaps through a comprehensive, Africa‑anchored Observatory, with pathogen genomics serving as an initial pilot use case.

This RFP is explicitly focused on Challenge I – demand consolidation and market visibility, which was identified as a foundational and enabling gap across the broader procurement and supply chain ecosystem. Progress on the remaining challenge areas will require continued collaboration and complementary investments from governments, regional institutions, additional funders, and implementing partners, building on the shared roadmap established through the convening.

A key and immediate gap is the lack of reliable, shared market intelligence including price transparency, supplier visibility, and aggregated demand signals. Addressing this gap is critical to improving procurement efficiency and enabling more coordinated, data-driven decision making across the ecosystem.

To address this challenge, this RFP under the "African R&D Procurement and Supply Chain Initiative" titled "Establishment of an African Procurement and Supply Chain Observatory for Public Health and R&D Reagents and Laboratory Supplies" seeks to establish a procurement and supply chain observatory (the "Observatory") to significantly improve market transparency, coordination, and decision-making across the African procurement ecosystem.

Through this RFP, partners will be selected for two critical roles:

  • Option A: A Platform Hosting Institution to lead governance and ensure the Observatory operates as a neutral and trusted entity, and
  • Option B: A Technical Architecture and Systems Integration partner or consortium of partners to define technical specifications and design and build the platform.

The Challenge

This Grand Challenges RFP seeks to support the implementation of a neutral, disease and method agnostic, trusted, and interoperable Procurement and Supply Chain Observatory (the "Observatory") to strengthen R&D reagents and laboratory supplies, initially starting with pathogen genomics. The Observatory will aggregate demand, enhance market transparency, and efficiently connect buyers with suppliers. Ultimately, this initiative will translate into consolidated purchasing power, shorter lead times, and more responsive after-sales support.

A core principle of the Observatory is technical and market neutrality, ensuring that the platform is designed as a regularly updated public good, accessible to all, free from bias toward any specific vendor, technology stack, or commercial interest.

Phase I will focus on building the market visibility and intelligence foundation, including price transparency, supplier and product visibility, and demand signals for priority product categories (initially Pathogen Genomic Sequencing focused). In this phase, the technical architecture, system requirements, and integration strategy will be defined for subsequent platform development, which will be implemented in Phase II.

This approach will empower researchers and public health institutions to deliver on their mandate, enable suppliers to grow sustainably, and ensure governments and funders maximize the value of their investments.

The Observatory will be developed in two phases:

Phase I

  1. Enhance Market Visibility: Provide structured, assessable data on demand, including supplier capabilities, pricing, and lead times for critical laboratory inputs from reagents to equipment.
  2. Improve Price Transparency: Enable cross-country price benchmarking, identify price variability and inefficiencies, and support evidence-based planning and negotiation.
  3. Strengthen Demand Intelligence and Forecasting: Aggregate non-binding demand signals across institutions and countries and strengthen demand planning capabilities to support improved forecasting, reduce stock-outs, and minimize wastage.
  4. Generate Market Intelligence and Analytics: Monitor and visualize key supply chain performance indicators, including stock-out trends, supplier concentration, and price movements, to support data-driven decision-making across the ecosystem.
  5. Inform Policy and Market-Shaping Interventions: Generate actionable insights to support regulatory harmonization, inform policy decisions, and guide market-shaping interventions
  6. Consider System Integration and Ecosystem Interoperability: Integrate with procurement platforms, logistics systems, and national health and laboratory systems and interoperability with existing regional and global platforms to enable seamless data exchange and coordination.
  7. Develop a financial sustainability plan for the Observatory: beyond the end of this Gates Foundation investment. The sustainability plan will be reviewed and agreed upon with stakeholders and the Gates Foundation before Phase II begins, and it will subsequently be implemented as part of Phase II activities.

Phase II (Subject to Validation and Scale)

Building on Phase I, the Observatory may progressively expand to support enhanced coordination, visibility, and system integration across the procurement and supply chain ecosystem.

This may include:

1. Demand Coordination and Aggregation

  • Coordinated demand planning across institutions and countries
  • Aggregated demand signals to support pooled procurement and improved supplier engagement

2. Buyer–Supplier Visibility and Coordination

  • Improved visibility between buyers and suppliers
  • Structured mechanisms to support supplier discovery and engagement, including local and regional manufacturers

3. Procurement Coordination (Non-Transactional to Light Enablement)

  • Support for bundled purchasing and coordinated procurement approaches
  • Facilitation of aligned procurement cycles and contracting approaches (without direct transaction execution in early stages)

4. Service and Lifecycle Visibility

  • Visibility into installation, maintenance, and after-sales service requirements
  • Coordination of service schedules and spare parts planning to improve equipment uptime and sustainability

5. Order and Fulfilment Visibility

  • Visibility into order status and fulfillment progress across key stages, including:
    • manufacturing
    • shipment
    • customs clearance
    • delivery

The scope and sequencing of these capabilities will be guided by validated user needs, system readiness, and lessons from the initial phase.

Science for Africa Foundation (SFA) will serve as the overall lead of the Observatory blueprint while also continuing its advocacy efforts to advance the remaining three priority challenges. Independently funded, SFA provides the critical bridge between the technical development of the platform and the diverse ecosystem of stakeholders and end-users across the continent. Their role includes coordinating stakeholder engagement, defining system requirements, and facilitating alignment between end-users, the host institution, and the technical partners ensuring the tool remains responsive to the needs of scientists and public health institutions in Africa.

To support SFA towards establishing the Observatory blueprint, we are looking for two separate but complementary partners with clearly defined and coordinated implementation roles:

  1. The Observatory Platform Hosting Institution ("Option A")
  2. Technical Architecture and Systems Integration partner or consortium of partners ("Option B")

These partners will work in close coordination with SFA, as they develop the Observatory blueprint through stakeholder engagement, define system requirements, and ensure alignment with user needs. The blueprint will help define system architecture, specifications, and validation plans. After the blueprint is developed, the selected partners should ensure clear implementation of milestones and regularly assess and report on delivery.

Collaboration Between Partners

The Hosting Institution and the Technical Architecture and Systems Integration Partner will work in close coordination initially under the leadership of SFA.

  • SFA will provide overall oversight, convene stakeholders and guide system definitions, and set up governance for the first 12 months.
  • The Technical Partner will lead architecture, system design, validation, and platform development.
  • The Hosting Institution will provide governance, stewardship, and oversight after the system is validated and transitioned from the technical partner.

All major system design decisions will be reviewed and validated collaboratively in consultation with the funders and end-users.

Independent Track Selection Process:

This RFP seeks to identify 2 separate entities for distinct roles:

  • Option A: Observatory Platform Hosting Institution
  • Option B: Technical Architecture and Systems Integration Partner

Organizations should apply independently with proposals meeting the criteria for either Option A or Option B. Joint applications between Platform Hosting Institution ("Option A") and Technical Architecture and Systems Integration Partner ("Option B") will not be accepted in this round. However, coordination between applicants is strongly encouraged. Following selection, there will be a structured matching and alignment process between the selected partners prior to the final award activation.

See full details for each track within the tables below.

Eligibility Criteria: 

To ensure continuity from the stakeholder meeting held in June 2025, the application process is structured around the following criteria:

  • Applications for this Grand Challenges RFP are by invitation only, with a limit of one proposal per institution. Consortia of institutions or applicants are strongly encouraged for Option B.
  • This Grand Challenge is open to the following types of organizations: non-profit organizations, for-profit companies, academic, research institutions, international organizations, and consortia.
  • Individuals and entities treated as individuals for U.S. tax purposes are not eligible for awards under this initiative.

Funding Level:

  • Option A (Observatory Platform Hosting Institution): We will consider proposals requesting up to $750,000 USD with a grant term of up to 36 months.
  • Option B (Technical Architecture and Systems Integration Partner): We will consider proposals requesting up to $1,500,000 USD in total funding, comprising up to $500,000 USD for Phase I and up to $1,000,000 USD for Phase II, over a grant term of up to 24 months. Continued funding for the Technical Architecture and Systems Integration Partner beyond Phase I will be subject to sufficient performance, validation, and achievement of technical and operational milestones. For the estimated start date, please refer to the Rules and Guidelines for this RFP.

Application budgets should be commensurate with the scope of work being proposed. Indirect costs are allowable and should be included within the total requested funding (subject to the Gates Foundation's indirect cost policy).

Timelines:

  • Option A (Observatory Platform Hosting Institution): Proposals for the host institution should clearly show the proposed activities to be carried out alongside the technical developer and SFA:
    • Participate in SFA organized or other advisory panels and convenings, set up a secretariat in readiness for platform hosting, engage with key partners to promote ownership and ultimately usability across the continent, and develop a sustainability plan (12 months).
    • Assume custodianship and Observatory implementation (24 months).
  • Option B (Technical Architecture and Systems Integration Partner): Proposals from the technical developer should provide a milestone-based iterative approach for the first 12 months:
    • Together with SFA agree and sign off on the Observatory blueprint by June 2027 (12 months).
    • Develop and present a tested MVP by December 2027 (18 months).
    • Iterate and transition platform to host by June 2028 (24 months)

Track Details:

Option A: The Observatory Platform Hosting Institution

The hosting organization will act as the system steward, normative authority, and trusted custodian to ensure the Observatory delivers long-term public value to Africa’s R&D and public health laboratory supplies, reagents, and consumables. To balance legitimacy, usability, and ultimately user ownership it is preferred that an African public health regional body takes up this role.

We are looking for a hosting organization that will:

Provide Strategic Stewardship and System Integrity
  • Safeguard the mission and public-good nature of the Observatory.
  • Develop governing frameworks and set up the various governance bodies.
  • Ensure long-term alignment with:
    • Continental public health and R&D priorities.
    • Regulatory harmonization efforts (e.g., AMA, AfCFTA).
    • Research scientists and institutional needs.
    • Other relevant procurement and supply chain platforms that already exist and those that are under development.
    • Periodically review whether the platform addresses the most critical procurement and supply-chain bottlenecks.
  • Safeguard vendor capture and misuse of the platform for commercial interests.
  • Ensure that all system architecture and technology decisions remain vendor-neutral and aligned with public-good principles.
  • Provide operational oversight during the implementation in Phase I, ensuring milestones are met across technical and stakeholder engagement workstreams.
  • Coordinate between various governance bodies, technical working groups, and regulatory actors to ensure a unified approach.
  • Set up a lean agile team to support the above-mentioned work.
Provide Oversight for Normative Functions and Standards Setting
  • In alignment with global, regional, and country regulations, define and maintain common standards for:
    • Product taxonomy and specifications (reagents, consumables, equipment, services).
    • Supplier eligibility and quality thresholds.
    • Demand, pricing, lead-time, and service-level definitions.
  • Endorse alignment with recognized quality and regulatory benchmarks (e.g., WHO prequalification).
  • Promote best practices in:
    • Demand aggregation.
    • Forecasting.
    • Pooled and bundled procurement.
Provide Data Stewardship and Trust Architecture
  • Act as the trusted custodian of system-level data, not a commercial data owner.
  • Approve and enforce data governance policies covering:
    • Data collection, storage, and use.
    • Tiered access to sensitive demand and pricing information.
    • Anonymization and aggregation rules.
  • Ensure compliance with:
    • Country and regional data protection requirements.
    • Ethical use of market and procurement data.
  • Authorize use of data for:
    • Market intelligence products.
    • Policy analysis.
    • Donor and country decision-making.
Provide Market Stewardship and Ecosystem Development
  • Monitor market health indicators, including:
    • Price volatility.
    • Stock-out frequency.
    • Supplier concentration and single-source risks.
  • Identify and signal market gaps and vulnerabilities to:
    • Funders.
    • Manufacturers.
    • Regional industrial and trade actors.
  • Promote local and regional manufacturers, distributors, and service providers.
Collaborate in Partnership Management
  • Partner with SFA during Observatory blueprint development in convening key stakeholders, gather information on user needs, and use these inputs to define observatory specifications and guide the development phase.
  • Work closely with SFA to put together a sustainability plan for the Observatory.
Provide Oversight for Accountability, Learning and Performance of the Observatory
  • Define and track system-level performance indicators, such as:
    • Changes in procurement lead times.
    • Price trends for priority R&D inputs.
    • Forecast accuracy improvements.
    • Supplier performance and reliability.
  • Commission or oversee:
    • Independent evaluations.
    • Periodic user feedback and satisfaction assessments.
  • Use evidence and learning to:
    • Adapt platform strategy.
    • Inform policy and market-shaping recommendations.
  • Support resource mobilization and sustainability of the platform beyond 18 months.
What the hosting organization is not expected to do
  • Manage day-to-day procurement or transactions
  • Monetize or commercially exploit platform data
  • Compete with private procurement, logistics, or service providers
  • Independently build or operate all technical platform components

 

Option B: A Technical Architecture and Systems Integration Partner

The Technical Architecture and Systems Integration Partner will serve as the lead technical entity responsible for system architecture design, specification development, and platform implementation, ensuring interoperability, modularity, and alignment with the Observatory’s public-good objectives. While the procurement and supply chain issues cut across public health and R&D efforts on the continent, the successful proposal will initially pilot on using Pathogen Genomic Sequencing as a use case.

We are seeking proposals that outline a milestone-based approach to achieving the deliverables described in Phases I and II above. Proposals should include clearly defined milestones across the following areas, including but not limited to:

  1. Architecture, system design, and validation.
  2. Platform development, integration, and deployment.

The technical partner will participate in user engagements conversations that will inform the Observatory blueprint which they will implement as a neutral architecture function, ensuring that all system design decisions are modular, interoperable, and not biased toward any specific technology stack, proprietary solution, or vendor.

The partners will operate under the strategic direction and partnership of an advisory panel, ensuring that the platform meets real-world user needs while aligning with regional health priorities, regulatory processes, and public-sector workflows.

The successful technical developer will be technically agile, user-centered, and with ability to make rapid iterations, while ensuring that the Observatory evolves into a robust, scalable, secure, sustainable, Africa-owned digital global public good.

The successful partner will demonstrate:

  • Strong system architecture and integration capabilities.
  • Ability to operate in complex, multi-country environments.
  • Experience delivering modular, scalable, and interoperable platforms.
  • A user-centered and iterative development approach.

We are looking for a Technical Architecture and Systems Integration partner that will:

Collaboratively Define the Technical Specifications, building from the Observatory Blueprint
  • Lead end-to-end‑ technical design and development of the Observatory platform.
  • Lead landscape mapping across relevant platforms (e.g., procurement, laboratory, and supplier system) and specification discussions at convenings organized and led by SFA and attended by the host organization.
  • Translate stakeholder needs into system requirements as defined in the Observatory blueprint, in collaboration with SFA, the host organization, and end-users.
  • Develop a modular, scalable, and interoperable architecture aligned with open standards and APIs building on existing procurement and laboratory systems.
  • Ensure the platform supports:
    • Market visibility: Supplier and product catalogs, indicative pricing, regulatory status, and lead times.
    • Demand aggregation: Tools to consolidate demand across institutions and countries, using standardized universal HS codes.
    • Monitoring, analyses, and visualization of key performance metrics.
  • Design Principles: Apply User-Centered Design to create low-bandwidth, mobile-friendly, and multilingual interfaces that reflect actual laboratory and procurement workflows.
  • To ensure the observatory is efficient, easy to use, and sustainable, the following cross-cutting areas will need to be integrated:
    • Governance and trust: Clear rules on data use, supplier vetting, and pricing transparency.
    • Interoperability: Integration with existing country procurement systems and institutional workflows through open APIs.
    • User-centered design: Low-bandwidth, mobile-friendly, multilingual interfaces tailored to diverse users.
    • Logistics and last-mile visibility: Indicative timelines for manufacturing, shipping, customs clearance, and delivery.
    • Market-shaping analytics: Identification of fragile markets, chronic shortages, and opportunities for regional manufacturing.
    • Modular and expandable for other goods and use-cases
Technical Hosting and Platform Management During Development Phase

During the development and pilot phase, the Technical Architecture and Systems Integration Partner will:

  • Build the Observatory platform based on validated architecture and SRS.
  • Integrate with existing systems through APIs and interoperability standards.
  • Host and manage development, staging, and production environment.
  • Multilingual and low-connectivity access: Design for multilingual user interfaces and offline/low‑bandwidth functionality (e.g., offline data capture with secure synchronization when connectivity is available), ensuring usability across diverse operating contexts.
  • Maintain development, staging, and production environments as appropriate.
  • Security and Data Protection: Implement robust data security (at rest and in transit), multi-factor authentication (MFA), and ensure compliance with regional data protection laws.
  • Quality Assurance (QA): Lead rigorous automated and manual testing, including security penetration testing and load testing for high-traffic scenarios.
  • Establish automated backup protocols and a clear Disaster Recovery Plan (DRP) to ensure business continuity.
  • Ensure performance and scalability.

This arrangement enables flexibility and speed while minimizing early operational burden on the hosting institution.

Collaboration and Coordination with hosting institution and SFA

 

The Technical Architecture and Systems Integration Partner will continuously work in close coordination with the platform hosting institution and SFA and provide technical leadership in the development of the Observatory blueprint by:

  • Participating in regular joint design and review sessions organized by SFA or other relevant stakeholders
  • Incorporating policy, regulatory, and operational considerations into system design.
  • Supporting SFA led and other relevant stakeholder consultations and country engagements to define the platform specifications and develop a phased-out iterative milestone timeline.
  • Adapting platform functionality based on feedback from key stakeholders such as scientists and laboratory users, procurement agencies, manufacturers, and service providers.
Knowledge Transfer and Capacity Building

A core responsibility of the Technical Architecture and Systems Integration Partner is to ensure a smooth and complete transition of the Observatory to the host institution. This includes:

  • Comprehensive documentation of:
    • System architecture.
    • Codebase and APIs.
    • Security protocols.
    • Operational and maintenance workflows.
    • User manuals
  • Training host institution staff responsible for:
    • System administration.
    • User support.
    • Routine technical maintenance.
  • Supporting joint onboarding sessions for participating institutions and users.
Structured Platform Handover (The "Exit Strategy")

Following full development, launch, and validation, the Technical Architecture and Systems Integration Partner will support a structured handover to the host, including:

  • Propose a defined co-management period, during which:
    • The host institution progressively assumes full operational responsibility.
    • The developer provides dedicated technical support and troubleshooting.
  • Ensure full transfer of code, documentation, and system ownership to the hosting organization.
  • Final verification that the host can independently operate, maintain, and evolve the platform.
  • Ensure all code, assets, and data are legally and technically transferred as a Digital Public Good, free of proprietary lock-ins.
The Technical Architecture and Systems Integration Partner will not:
  • Own or govern the Observatory.
  • Propose or deploy a pre-existing or proprietary platform as the Observatory solution, nor shape system requirements to align with an existing product or internal technology stack.
  • Set procurement policy or regulatory rules.
  • Control access to or commercialize platform data.
  • Operate the platform as a private marketplace beyond agreed development responsibilities.

Evaluation Metrics and Criteria 

 

Progress will be evaluated by:

  • Commitment to participate in stakeholder engagement organized by SFA and if needed, to also organize additional engagements with end users and/or stakeholders.
  • System Requirements Specification (SRS): The SRS is expected to describe, at a high level, the system architecture, functional and non‑functional requirements, data flows, user roles, security considerations, interoperability expectations, and operational assumptions. The document should also provide indicative specifications related to performance, scalability, maintenance, and support models, recognizing that these elements may continue to evolve during the development process based on stakeholder input and technical feasibility assessments. The SRS must demonstrate a modular, vendor-neutral architecture that avoids proprietary lock-in and supports integration with multiple systems and future technology partners.
  • User Requirement Specification: Outlining a translation of operational workflows, stakeholder needs, and compliance obligations into clear and testable functional and non-functional requirements and covering user roles, use cases, data inputs and outputs, performance expectations, security and regulatory constraints, interoperability needs, and reporting requirements. The URS document will be used for validation, user acceptance testing, and ensuring that the final solution aligns with the planned observatory objectives and user workflows.
  • Architecture and Technology Strategy
    • A structured approach outlining:
      • Build vs adapt vs integrate decisions
      • Proposed system architecture and component breakdown
      • Identification of required technology capabilities and potential partner types
      • Justification of design choices against alternatives
  • The proposal must demonstrate how neutrality will be maintained in architecture design and technology selection.
  • Minimum Viable Product (MVP) and Prototype Plan for the development and provision of an initial prototype and MVP for the observatory platform. The prototype and MVP are intended to demonstrate the core Phase I functional capabilities of the system and support early user testing, technical validation, and iterative refinement.
  • A fully functional observatory platform: Detailed description of the finalized version of the observatory platform, developed and prepared for operational deployment. The final product is expected to reflect the core functionality, technical specifications, and user experience features agreed upon during the development process
  • A clear Platform Development and Implementation Approach:
    • Building the platform based on validated specifications
    • Integration with existing systems
    • Deployment and scale-up strategy
  • Note progression to Phase II will be contingent on validation of Phase I milestones (SRS, architecture, and MVP).
  • Detailed Plan for Transfer and Hosting of the Observatory: Detailed description of the anticipated process, technical and operational requirements, and capacity‑building considerations associated with transitioning the observatory platform to the hosting institution for long‑term hosting and maintenance workflows and troubleshooting guides. The plan must ensure no proprietary lock-in and full transfer of system ownership.
  • Cost-Effectiveness and Sustainability Model: A detailed description of Value-for-Money (VfM) proposal, which should outline:
    • Efficiency in resource allocation during the development phase.
    • A sustainable financial and operational model for the platform's post-launch lifespan.
    • A collaborative approach that maximizes shared value across the partnership ecosystem.
    • Assumptions on long-term funding, operational ownership, and cost drivers.

 

 

Share this content