Establishment of an African Procurement and Supply Chain Observatory for Public Health and R&D Reagents and Laboratory Supplies

Before applying to this Grand Challenges request for proposals (RFP), applicants should familiarize themselves with the supporting documents, including the terms and conditions of the Gates Foundation, the Rules and Guidelines, Application Instructions, and Frequently Asked Questions.
If you are planning to apply to this RFP, we will be hosting a dedicated webinar on April 29, 2026, from 8:00-9:00 AM Pacific Time. This session will provide a comprehensive overview of the RFP details and an opportunity to answer your questions. To participate in the webinar, please register and submit your questions in advance. If you are unable to attend live, we will record the webinar and make it available on this challenge page after the session.
Background
Public health and R&D institutions across Africa face persistent, systemic challenges in procuring essential laboratory equipment, reagents, consumables, and related services. The market for these products and services suffers from fragmented demand, inadequate forecasting, limited market visibility, complex and inconsistent regulatory processes, inflated prices, and a lack of reliable and timely after-sales support. These inefficiencies can drive high costs, extended lead times, frequent stock-outs, and missed research and public health surveillance milestones.
In June 2025, Science for Africa Foundation convened a diverse set of stakeholders, including researchers, manufacturers, suppliers, distributors, and digital and technical experts for a two-day design workshop. This meeting identified four priority challenges and proposed solution areas:
- Challenge I: Demand consolidation and market visibility; alternative procurement models
- Challenge II: Local manufacturing and uptake
- Challenge III: Trade facilitation and customs harmonization
- Challenge IV: Innovative sample transportation
As a follow-up to the June stakeholder convening, the Science for Africa Foundation (SFA), in partnership with the Gates Foundation and Wellcome, is launching the African R&D Procurement and Supply Chain Initiative, a coordinated portfolio of efforts aimed at strengthening Africa’s research and innovation ecosystem. The initiative initially focuses on pathogen genomics as a pilot use case. As a cornerstone component of this, Wellcome will be supporting SFA to convene key African organizations and global stakeholders to develop an implementation-ready blueprint for an Africa-anchored Observatory with pathogen genomics supply chain as a use case. With this RFP, the Gates Foundation will fund its implementation.
This RFP and the broader initiative build on a range of existing procurement and supply chain platforms and initiatives. While these platforms have delivered or are delivering important impact, they were not designed to address several persistent system‑level challenges across the full spectrum of public health and R&D. These include the absence of consolidated demand intelligence across institutions and countries, limited visibility into pricing and lead‑time variability, fragmented supplier and product information, and a lack of coordinated market‑shaping analytics. As a result, institutions continue to face high and inconsistent prices, long lead times, and insufficient transparency. This RFP directly targets these unmet gaps through a comprehensive, Africa‑anchored Observatory, with pathogen genomics serving as an initial pilot use case.
This RFP is explicitly focused on Challenge I – demand consolidation and market visibility, which was identified as a foundational and enabling gap across the broader procurement and supply chain ecosystem. Progress on the remaining challenge areas will require continued collaboration and complementary investments from governments, regional institutions, additional funders, and implementing partners, building on the shared roadmap established through the convening.
A key and immediate gap is the lack of reliable, shared market intelligence including price transparency, supplier visibility, and aggregated demand signals. Addressing this gap is critical to improving procurement efficiency and enabling more coordinated, data-driven decision making across the ecosystem.
To address this challenge, this RFP under the "African R&D Procurement and Supply Chain Initiative" titled "Establishment of an African Procurement and Supply Chain Observatory for Public Health and R&D Reagents and Laboratory Supplies" seeks to establish a procurement and supply chain observatory (the "Observatory") to significantly improve market transparency, coordination, and decision-making across the African procurement ecosystem.
Through this RFP, partners will be selected for two critical roles:
- Option A: A Platform Hosting Institution to lead governance and ensure the Observatory operates as a neutral and trusted entity, and
- Option B: A Technical Architecture and Systems Integration partner or consortium of partners to define technical specifications and design and build the platform.
The Challenge
This Grand Challenges RFP seeks to support the implementation of a neutral, disease and method agnostic, trusted, and interoperable Procurement and Supply Chain Observatory (the "Observatory") to strengthen R&D reagents and laboratory supplies, initially starting with pathogen genomics. The Observatory will aggregate demand, enhance market transparency, and efficiently connect buyers with suppliers. Ultimately, this initiative will translate into consolidated purchasing power, shorter lead times, and more responsive after-sales support.
A core principle of the Observatory is technical and market neutrality, ensuring that the platform is designed as a regularly updated public good, accessible to all, free from bias toward any specific vendor, technology stack, or commercial interest.
Phase I will focus on building the market visibility and intelligence foundation, including price transparency, supplier and product visibility, and demand signals for priority product categories (initially Pathogen Genomic Sequencing focused). In this phase, the technical architecture, system requirements, and integration strategy will be defined for subsequent platform development, which will be implemented in Phase II.
This approach will empower researchers and public health institutions to deliver on their mandate, enable suppliers to grow sustainably, and ensure governments and funders maximize the value of their investments.
The Observatory will be developed in two phases:
Phase I
- Enhance Market Visibility: Provide structured, assessable data on demand, including supplier capabilities, pricing, and lead times for critical laboratory inputs from reagents to equipment.
- Improve Price Transparency: Enable cross-country price benchmarking, identify price variability and inefficiencies, and support evidence-based planning and negotiation.
- Strengthen Demand Intelligence and Forecasting: Aggregate non-binding demand signals across institutions and countries and strengthen demand planning capabilities to support improved forecasting, reduce stock-outs, and minimize wastage.
- Generate Market Intelligence and Analytics: Monitor and visualize key supply chain performance indicators, including stock-out trends, supplier concentration, and price movements, to support data-driven decision-making across the ecosystem.
- Inform Policy and Market-Shaping Interventions: Generate actionable insights to support regulatory harmonization, inform policy decisions, and guide market-shaping interventions
- Consider System Integration and Ecosystem Interoperability: Integrate with procurement platforms, logistics systems, and national health and laboratory systems and interoperability with existing regional and global platforms to enable seamless data exchange and coordination.
- Develop a financial sustainability plan for the Observatory: beyond the end of this Gates Foundation investment. The sustainability plan will be reviewed and agreed upon with stakeholders and the Gates Foundation before Phase II begins, and it will subsequently be implemented as part of Phase II activities.
Phase II (Subject to Validation and Scale)
Building on Phase I, the Observatory may progressively expand to support enhanced coordination, visibility, and system integration across the procurement and supply chain ecosystem.
This may include:
1. Demand Coordination and Aggregation
- Coordinated demand planning across institutions and countries
- Aggregated demand signals to support pooled procurement and improved supplier engagement
2. Buyer–Supplier Visibility and Coordination
- Improved visibility between buyers and suppliers
- Structured mechanisms to support supplier discovery and engagement, including local and regional manufacturers
3. Procurement Coordination (Non-Transactional to Light Enablement)
- Support for bundled purchasing and coordinated procurement approaches
- Facilitation of aligned procurement cycles and contracting approaches (without direct transaction execution in early stages)
4. Service and Lifecycle Visibility
- Visibility into installation, maintenance, and after-sales service requirements
- Coordination of service schedules and spare parts planning to improve equipment uptime and sustainability
5. Order and Fulfilment Visibility
- Visibility into order status and fulfillment progress across key stages, including:
- manufacturing
- shipment
- customs clearance
- delivery
The scope and sequencing of these capabilities will be guided by validated user needs, system readiness, and lessons from the initial phase.
Science for Africa Foundation (SFA) will serve as the overall lead of the Observatory blueprint while also continuing its advocacy efforts to advance the remaining three priority challenges. Independently funded, SFA provides the critical bridge between the technical development of the platform and the diverse ecosystem of stakeholders and end-users across the continent. Their role includes coordinating stakeholder engagement, defining system requirements, and facilitating alignment between end-users, the host institution, and the technical partners ensuring the tool remains responsive to the needs of scientists and public health institutions in Africa.
To support SFA towards establishing the Observatory blueprint, we are looking for two separate but complementary partners with clearly defined and coordinated implementation roles:
- The Observatory Platform Hosting Institution ("Option A")
- Technical Architecture and Systems Integration partner or consortium of partners ("Option B")
These partners will work in close coordination with SFA, as they develop the Observatory blueprint through stakeholder engagement, define system requirements, and ensure alignment with user needs. The blueprint will help define system architecture, specifications, and validation plans. After the blueprint is developed, the selected partners should ensure clear implementation of milestones and regularly assess and report on delivery.
Collaboration Between Partners
The Hosting Institution and the Technical Architecture and Systems Integration Partner will work in close coordination initially under the leadership of SFA.
- SFA will provide overall oversight, convene stakeholders and guide system definitions, and set up governance for the first 12 months.
- The Technical Partner will lead architecture, system design, validation, and platform development.
- The Hosting Institution will provide governance, stewardship, and oversight after the system is validated and transitioned from the technical partner.
All major system design decisions will be reviewed and validated collaboratively in consultation with the funders and end-users.
Independent Track Selection Process:
This RFP seeks to identify 2 separate entities for distinct roles:
- Option A: Observatory Platform Hosting Institution
- Option B: Technical Architecture and Systems Integration Partner
Organizations should apply independently with proposals meeting the criteria for either Option A or Option B. Joint applications between Platform Hosting Institution ("Option A") and Technical Architecture and Systems Integration Partner ("Option B") will not be accepted in this round. However, coordination between applicants is strongly encouraged. Following selection, there will be a structured matching and alignment process between the selected partners prior to the final award activation.
See full details for each track within the tables below.
Eligibility Criteria:
To ensure continuity from the stakeholder meeting held in June 2025, the application process is structured around the following criteria:
- Applications for this Grand Challenges RFP are by invitation only, with a limit of one proposal per institution. Consortia of institutions or applicants are strongly encouraged for Option B.
- This Grand Challenge is open to the following types of organizations: non-profit organizations, for-profit companies, academic, research institutions, international organizations, and consortia.
- Individuals and entities treated as individuals for U.S. tax purposes are not eligible for awards under this initiative.
Funding Level:
- Option A (Observatory Platform Hosting Institution): We will consider proposals requesting up to $750,000 USD with a grant term of up to 36 months.
- Option B (Technical Architecture and Systems Integration Partner): We will consider proposals requesting up to $1,500,000 USD in total funding, comprising up to $500,000 USD for Phase I and up to $1,000,000 USD for Phase II, over a grant term of up to 24 months. Continued funding for the Technical Architecture and Systems Integration Partner beyond Phase I will be subject to sufficient performance, validation, and achievement of technical and operational milestones. For the estimated start date, please refer to the Rules and Guidelines for this RFP.
Application budgets should be commensurate with the scope of work being proposed. Indirect costs are allowable and should be included within the total requested funding (subject to the Gates Foundation's indirect cost policy).
Timelines:
- Option A (Observatory Platform Hosting Institution): Proposals for the host institution should clearly show the proposed activities to be carried out alongside the technical developer and SFA:
- Participate in SFA organized or other advisory panels and convenings, set up a secretariat in readiness for platform hosting, engage with key partners to promote ownership and ultimately usability across the continent, and develop a sustainability plan (12 months).
- Assume custodianship and Observatory implementation (24 months).
- Option B (Technical Architecture and Systems Integration Partner): Proposals from the technical developer should provide a milestone-based iterative approach for the first 12 months:
- Together with SFA agree and sign off on the Observatory blueprint by June 2027 (12 months).
- Develop and present a tested MVP by December 2027 (18 months).
- Iterate and transition platform to host by June 2028 (24 months)
Track Details:
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Option A: The Observatory Platform Hosting Institution The hosting organization will act as the system steward, normative authority, and trusted custodian to ensure the Observatory delivers long-term public value to Africa’s R&D and public health laboratory supplies, reagents, and consumables. To balance legitimacy, usability, and ultimately user ownership it is preferred that an African public health regional body takes up this role. We are looking for a hosting organization that will: |
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| Provide Strategic Stewardship and System Integrity |
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| Provide Oversight for Normative Functions and Standards Setting |
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| Provide Data Stewardship and Trust Architecture |
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| Provide Market Stewardship and Ecosystem Development |
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| Collaborate in Partnership Management |
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| Provide Oversight for Accountability, Learning and Performance of the Observatory |
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| What the hosting organization is not expected to do |
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Option B: A Technical Architecture and Systems Integration Partner The Technical Architecture and Systems Integration Partner will serve as the lead technical entity responsible for system architecture design, specification development, and platform implementation, ensuring interoperability, modularity, and alignment with the Observatory’s public-good objectives. While the procurement and supply chain issues cut across public health and R&D efforts on the continent, the successful proposal will initially pilot on using Pathogen Genomic Sequencing as a use case. We are seeking proposals that outline a milestone-based approach to achieving the deliverables described in Phases I and II above. Proposals should include clearly defined milestones across the following areas, including but not limited to:
The technical partner will participate in user engagements conversations that will inform the Observatory blueprint which they will implement as a neutral architecture function, ensuring that all system design decisions are modular, interoperable, and not biased toward any specific technology stack, proprietary solution, or vendor. The partners will operate under the strategic direction and partnership of an advisory panel, ensuring that the platform meets real-world user needs while aligning with regional health priorities, regulatory processes, and public-sector workflows. The successful technical developer will be technically agile, user-centered, and with ability to make rapid iterations, while ensuring that the Observatory evolves into a robust, scalable, secure, sustainable, Africa-owned digital global public good. The successful partner will demonstrate:
We are looking for a Technical Architecture and Systems Integration partner that will: |
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| Collaboratively Define the Technical Specifications, building from the Observatory Blueprint |
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| Technical Hosting and Platform Management During Development Phase |
During the development and pilot phase, the Technical Architecture and Systems Integration Partner will:
This arrangement enables flexibility and speed while minimizing early operational burden on the hosting institution. |
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Collaboration and Coordination with hosting institution and SFA
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The Technical Architecture and Systems Integration Partner will continuously work in close coordination with the platform hosting institution and SFA and provide technical leadership in the development of the Observatory blueprint by:
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| Knowledge Transfer and Capacity Building |
A core responsibility of the Technical Architecture and Systems Integration Partner is to ensure a smooth and complete transition of the Observatory to the host institution. This includes:
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| Structured Platform Handover (The "Exit Strategy") |
Following full development, launch, and validation, the Technical Architecture and Systems Integration Partner will support a structured handover to the host, including:
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| The Technical Architecture and Systems Integration Partner will not: |
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Evaluation Metrics and Criteria
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Progress will be evaluated by:
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