Use of a Powerful Phage DNA Packaging Motor to Engineer Nanoparticle DNA Vaccines
Grand Challenges ExplorationsInfectious Diseases1 Nov 2010
Venigalla Rao of The Catholic University of America in the U.S. will develop and test a DNA vaccine for HIV that encapsulates multiple HIV envelope genes into bacteriophages that will target antigen presenting dendritic cells. If successful, this could lead to a powerful multivalent DNA vaccine delivery platform against many diseases.