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Use of a BET Antagonist to Control and Cure HIV Infection

Terri Finkel of The Children's Hospital of Philadelphia in the U.S. will test whether synthetic BET (bromodomains and extraterminal) protein antagonists can inhibit the replication of HIV and the establishment of latency, while also promoting the reactivation of latently infected cells. Such molecules could be used to control and cure HIV infection.

More information about Design New Approaches to Cure HIV Infection (Round 7)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.