<p>James Shorter of The University of Pennsylvania in the U.S. will engineer enzymes that disassemble protein fibrils found in semen, which are known to allow for the transmission of HIV infection. The ability to reverse fibril formation could block sexual transmission of HIV and provide a new weapon against the global HIV/AIDS pandemic.</p>


James Shorter of The University of Pennsylvania in the U.S. will engineer enzymes that disassemble protein fibrils found in semen, which are known to allow for the transmission of HIV infection. The ability to reverse fibril formation could block sexual transmission of HIV and provide a new weapon against the global HIV/AIDS pandemic.

Unleashing Protein Disaggregases to Prevent HIV Infection

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View the Grand Challenges partnership network

Great ideas come from everywhere.