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Trojan Horse Vaccines for HIV Based on Lentiviral Vectors Expressing Suicide Envelopes

To provoke an effective immune response against HIV, George Dickson of Royal Holloway -University of London will utilize HIV-based lentivectors encoded with a strong neutralizing epitope derived from tetanus toxin or influenza on its surface. By forcing production of such highly immunogenic and stable antigens, the immune system will respond with corresponding antibodies and control virus replication.

More information about Create New Ways to Prevent or Cure HIV Infection (Round 1)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.