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A Trick To Control Malaria: Manipulating the Mosquito Innate Immune Response

Sumi Biswas of the Jenner Institute, University of Oxford in the United Kingdom will test three components from the mosquito's innate signaling pathways for possible use in a malaria vaccine. Biswas will test whether immunizing mammal hosts with these components can induce strong antibodies, which can be passed along to mosquitoes to enhance the insect's innate immune response, thus leading to the death of the malaria parasite in the vector.

More information about Create New Ways to Protect Against Infectious Disease (Round 5)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.