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Targeting HIV Provirus with Novel Restriction Endonucleases

Russell Poulter of the University of Otago in New Zealand will test 'homing' endonucleases found in the genomes of some microbes for their ability to precisely cleave DNA at very specific sites. If successful, these nucleases could be suitable for cleaving and eliminating integrated HIV.

More information about Design New Approaches to Cure HIV Infection (Round 6)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.