Global Grand Challenges
  • Grant Opportunities
  • Challenges
  • Awards
  • Champions
  • Partnerships
  • News
  • About

Targeted pH-Gated Nanoparticle Anti-TB Drug Delivery System

Marcus Horwitz and colleagues at UCLA in the U.S. will develop and test a novel drug delivery system in which nanoparticles loaded with anti-TB drugs selectively target macrophages, and release the drugs intracellularly via a pH-dependent gate, allowing delivery of high concentrations on antibiotics into the host cells for Mycobacterium tuberculosis.

More information about Create Drugs and Delivery Systems to Limit Drug Resistance (Round 2)

Great ideas come from everywhere.

Sign up for email updates of the latest grant opportunities and awards.

View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.