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Systematic High-Throughput Screening of B-cell Repertoires

Thor Wagner of Seattle Children's Hospital in the U.S. will use high-throughput single-cell screening of activated B-cells from HIV patients on antiretroviral therapy in an effort to identify antibodies that bind specifically to HIV-infected cells. These antibodies could be used to develop antibody drug conjugates to kill HIV-infected cells.

More information about Design New Approaches to Cure HIV Infection (Round 7)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.