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Synthetic Probiotic to Identify and Prevent Cholera

Jim Collins, Ewen Cameron, and Peter Belenky of Boston University and Howard Hughes Medical Institute in the U.S. plan to engineer the probiotic bacterium Lactobacillus gasseri to detect and kill Vibrio cholerae in the human intestine. The probiotic could be supplied as an inexpensive lyophilized powder to endemic populations to prevent cholera.

More information about Apply Synthetic Biology to Global Health Challenges (Round 8)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.