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Sublingual Vaccination for Inducing Broad-Based Mucosal Immunity

Cecil Czerkinsky of the International Vaccine Institute in South Korea will test the efficacy of administering two approved vaccines sublingually - directly under the tongue. The team will attempt to produce not only antibody responses but also cytotoxic T cell responses in distant mucosal organs such as the lungs and reproductive tract. Sublingual vaccine administration could help improve vaccine delivery, compliance, and enhance immunity against a variety of pathogens.

More information about Create New Ways to Induce Mucosal Immunity (Round 3)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.