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Programmed Killing of Parasite Eggs by Probiotic Organisms

Tae Seok Moon from Washington University in the U.S. will develop a bacterial-based strategy to block the transmission of soil-transmitted helminth infections (intestinal worms), which occurs via parasite eggs present in human feces. They will engineer consumable probiotic bacteria that are designed to sense when they are excreted from the body and to subsequently release toxic substances designed to kill the parasite eggs in order to prevent disease transmission.

More information about New Approaches in Model Systems, Diagnostics, and Drugs for Specific Neglected Tropical Diseases (Round 10)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.