POLMITRANSVAC "Pollen Mimetic Transcutaneous Vaccination"

Carlos Alberto Guzman of the Helmholtz Centre for Infection Research in Germany with Claus-Michael Lehr and Steffi Hansen of the Helmholtz-Institute for Pharmaceutical Research will develop and test a vaccine platform that uses a nanoparticle that mimics pollen, which has been shown to be able to penetrate the skin through hair follicles. The nanoparticle will burst upon contact with human sweat, releasing adjuvants and antigens to deliver a vaccine by targeting dendritic cells that surround hair follicles.