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Non-Hormonal Female Contraceptive Targeting Egg-Specific Metalloprotease

John Herr of the University of Virginia in the U.S. will research the egg-specific membrane enzyme metalloprotease as a target for a non-hormonal female contraceptive. After determining the nature of the enzyme's catalytic pocket, a family of peptidomimetic compounds will be tested for their ability to bind to the enzyme and block its key role in egg fertilization.

More information about Create New Technologies for Contraception (Round 4)