Neurobiological Resilience Predicted with Salivary Stressome

Patrick De Boever of VITO in Belgium will study the effects of stress on neurodevelopment in children by building a database of biological markers of the stress response detected in saliva. They will generate comprehensive genetic and epigenetic profiles, such as DNA methylation patterns, of salivary samples taken after laboratory-controlled or environmental stress events from over 1000 children of a range of ages and backgrounds. The aim is to capture developmental changes in stress reactivity over time and use the profiles to predict the course of neurological development.