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Neurobiological Resilience Predicted with Salivary Stressome

Patrick De Boever of VITO in Belgium will study the effects of stress on neurodevelopment in children by building a database of biological markers of the stress response detected in saliva. They will generate comprehensive genetic and epigenetic profiles, such as DNA methylation patterns, of salivary samples taken after laboratory-controlled or environmental stress events from over 1000 children of a range of ages and backgrounds. The aim is to capture developmental changes in stress reactivity over time and use the profiles to predict the course of neurological development.

More information about Explore New Ways to Measure Fetal and Infant Brain Development (Round 13)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.