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Mis-Expression of Liver-Specific miRNAs to Eradicate Malaria

When malaria parasites infect different human cells, including liver and red blood cells, it is thought that microRNAs are important developmental cues that facilitate specific events in the parasite life cycle. Jen-Tsan Chi of Duke Medical Center in the U.S. will test whether expressing liver-specific microRNAs within red blood cells will trick the parasite into undergoing liver-stage development, leading to its death.

More information about Create New Tools to Accelerate the Eradication of Malaria (Round 2)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.