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Microfluidic Platform for Rapid Drug Resistant Screening

Daniel Irimia and Anh Hoang of Massachusetts General Hospital in the U.S. seek to develop a microfluidic device that can be used to screen anti-malarial drugs for the development of drug resistance with single cell resolution. The device will be validated using a subset of anti-malarial compounds from the Malaria Box. The ability to monitor single cells for resistance will greatly reduce the time needed to screen drugs for acquired resistance, allowing for much earlier and more accurate assessment of effective drugs to control and eradicate malaria.

More information about New Approaches for the Interrogation of Anti-Malarial Compounds (Round 9)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.