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Microbial Biosensor for Diagnosing Leishmaniasis

Darren Zhu of Synbiosys, LLC in the U.S. aims to produce a low-cost diagnostic platform that can rapidly diagnose leishmaniasis in field conditions. He will engineer a bacterium with cell surface receptors that are activated and amplified by the presence of Leishmania proteases to produce a colorimetric readout. This biologic system could be extended to the rapid diagnosis of other infectious diseases.

More information about Apply Synthetic Biology to Global Health Challenges (Round 7)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.