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Killing T. brucei by RNA Aptamer-Mediated Immobilization

T. brucei, the parasite that causes sleeping sickness, must continuously swim forward in human blood to evade immune responses. Arthur Günzl of the University of Connecticut Health Center in the U.S. will attempt to develop serum-stable RNA molecules to immobilize the parasite by interrupting the mechanism driving parasite motility.

More information about Create Drugs and Delivery Systems to Limit Drug Resistance (Round 2)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.