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Increased Stability and Immunogenicity of Bacterial Vaccines

Frank Robb of the University of Maryland, Baltimore in the U.S. will genetically integrate heat shock proteins from thermopilic organisms, which thrive at relatively high temperatures, into attenuated bacterial vaccines to try to enhance the viability and immunogenicity of these vaccines during the freeze-drying process. If successful, this method could enhance the delivery of low -cost, highly-effective vaccines without the need for refrigeration.

More information about Create New Ways to Protect Against Infectious Disease (Round 5)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.