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Improving the Immunogenicity of HIV Envelope Glycoproteins

Michel Gilbert of the National Research Council Canada will use the single-celled microorganism T. acidophilum to produce HIV proteins with unique sugar residues found only in archaebacteria such as T. acidophilum. By modifying these glycan structures to ones not recognized by humans, Gilbert hopes to elicit a stronger immune response against the virus.

More information about Create New Vaccines for Diarrhea, HIV, Malaria, Pneumonia, and Tuberculosis (Round 3)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.