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Improve Mucosal Immune Responses to Oral Typhoid Vaccine

Firdausi Qadri of International Centre for Diarrhoeal Disease Research (ICDDR,B) in Bangladesh proposes that the presence of parasites in the guts of people who receive enteric vaccines diminishes the resulting immune response. Qadri hopes that by providing children with antihelminthic and anti-giardiasis drugs prior to administration of an oral typhoid vaccine, a robust immune response can be mounted.

More information about Create New Ways to Protect Against Infectious Disease (Round 4)

Great ideas come from everywhere.

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.