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Hydrocarbon-Stapled GP41 Immunogens

Loren Walensky of the Dana-Farber Cancer Institute in the U.S. will apply a new chemical technology to engineer structurally stable HIV-1 antigens for vaccine development. Walensky will test whether preserving the critical biologically active shape of HIV-1 polypeptides will yield neutralizing antibodies upon vaccination with his laboratory's synthetic immunogens.

More information about Create New Vaccines for Diarrhea, HIV, Malaria, Pneumonia, and Tuberculosis (Round 2)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.