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A Household Yeast Biosensor for Cholera

Virginia Cornish and Nili Ostrov at Columbia University in the U.S. propose to engineer baker's yeast to produce the red tomato pigment lycopene when exposed to the cholera pathogen in drinking water. This safe and simple sensor could be inexpensively manufactured and highly effective for household monitoring of cholera in water by communities at risk for infection.

More information about Apply Synthetic Biology to Global Health Challenges (Round 7)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.