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Hivi: A Novel Weapon to Kill HIV

Chang Liu and Xiaohong Kong of Nankai University in China seek to develop a self-destructive virus vector called HIVi, which will express small interfering RNA to silence HIV in infected cells, and also replicate in a controlled manner to outcompete the HIV infection before turning itself off. The efficacy of HIVi in interfering with HIV will be assessed using a number of standard HIV cell-based assays.

More information about Create New Ways to Protect Against Infectious Disease (Round 4)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.