Fusogenic Nanoparticles for Combined Anti-HIV/Contraception
Samuel Wickline of Washington University in the U.S. will formulate a vaginal gel that contains nanoparticles which serve as decoys to attract both sperm and HIV. The nanoparticles will fuse with specific receptors in the sperm and virions, causing both to deliver their genetic material into the nanoparticles, which simultaneously delivers a peptide that incapacitates both targets.