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Fusogenic Nanoparticles for Combined Anti-HIV/Contraception

Samuel Wickline of Washington University in the U.S. will formulate a vaginal gel that contains nanoparticles which serve as decoys to attract both sperm and HIV. The nanoparticles will fuse with specific receptors in the sperm and virions, causing both to deliver their genetic material into the nanoparticles, which simultaneously delivers a peptide that incapacitates both targets.

More information about Create New Technologies for Contraception (Round 5)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.