Eradicating HIV from Infected Cells with a Trojan Integrase

Alessandro Ripalti of Azienda Ospedaliero-Universitaria di Bologna S.Orsola-Malpighi in Italy will attempt to produce an engineered HIV integrase, an enzyme produced by the virus to integrate itself into host chromosomes, and test its ability to instead cut the virus' DNA at its integration sites in the human genome.