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Enzyme-Free DNA Circuits for Signal Amplification and Diagnostic Assays

Andrew Ellington of the University of Texas at Austin in the U.S. proposes to improve enzyme-free DNA circuits by engineering circuit sensitivity and selectivity, ultimately creating multi-layered circuits that greatly amplify signal inputs. These robust amplifiers could be modularly introduced into a variety of point-of-care diagnostics.

More information about Point-of-Care Diagnostics

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.