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Enhancing TB Vaccines with Gene Silencing

Jinhee Lee and Gary Ostroff of the University of Massachusetts Medical School in the U.S. will test the idea of delivering small interfering RNA (siRNAs) via glucan particles in an oral TB vaccine formulation. The team will utilize the siRNAs' ability to block immunosuppressive signaling and amplify the immune response.

More information about Create New Vaccines for Diarrhea, HIV, Malaria, Pneumonia, and Tuberculosis (Round 3)